Philipp Hess

Philipp Hess

Chercheur en Phycotoxines

Laboratoire Phycotoxines (PDG-ODE-DYNECO-PHYC)

Contact par courriel

02 40 37 42 57

Fax : 02 40 37 40 26

Employeur : Ifremer

Site : Nantes

Adresse postale : Centre Atlantique - Rue de l'Ile d'Yeu - BP 21105 - 44311 Nantes Cedex 03

URL : http://annuaire.ifremer.fr/cv/17128/

ORCID orcid icon : 0000-0002-9047-1345

Fonctions actuelles

Chercheur sénior au sein du laboratoire phycotoxines

Directeur Adjoint de l' Institut Universitaire Mer et Littoral - IUML (FR 3473 CNRS / Université de Nantes / Ifremer)

 


Activités d’enseignements

Enseignement d'un cours M2 sur les phycotoxines à l'Université de Nantes


Sites Web

Listen to my Webinar on the use of High Resolution Mass Spectrometry for Marine Biotoxins:

http://view6.workcast.net/?pak=8718440540155734

(a simple inscription suffices to view the webinar)

 

Researcher ID


Jeux de données

2015

Kilcoyne Jane, Mccarron Pearse, Hess Philipp, Miles Christopher O. (2015). Supporting Information of effects of Heating on AZAs. SEANOE. http://doi.org/10.17882/41845


Bibliographie

2016

Reveillon Damien, Sechet Veronique, Hess Philipp, Amzil Zouher (2016). Production of BMAA and DAB by diatoms (Phaeodactylum tricornutum, Chaetoceros sp., Chaetoceros calcitrans and, Thalassiosira pseudonana) and bacteria isolated from a diatom culture. Harmful Algae, 58, 45-50. http://doi.org/10.1016/j.hal.2016.07.008
Zendong Suzie Zita, Bertrand Samuel, Herrenknecht Christine, Abadie Eric, Jauzein Cecile, Lemee Rodolphe, Gouriou Jeremie, Amzil Zouher, Hess Philipp (2016). Passive Sampling and High Resolution Mass Spectrometry for Chemical Profiling of French Coastal Areas with a Focus on Marine Biotoxins. Environmental Science & Technology, 50(16), 8522-8529. http://doi.org/10.1021/acs.est.6b02081
Mondeguer Florence, Lepinay Alexandra, Capiaux Herve, Turpin Vincent, Baron Regis, Hess Philipp, Lebeau Thierry (2016). First metabolomic approach of the epiphytic bacteria-marine diatom Haslea ostrearia relationships. OCEANEXT, Interdisciplinary Conference. 8-10 juin 2016, Nantes, France. http://archimer.ifremer.fr/doc/00342/45367/
Abadie Eric, Muguet Alexia, Berteaux Tom, Chomerat Nicolas, Hess Philipp, Roque D'Orbcastel Emmanuelle, Masseret Estelle, Laabir Mohamed (2016). Toxin and Growth Responses of the Neurotoxic Dinoflagellate Vulcanodinium rugosum to Varying Temperature and Salinity. Toxins, 8(5), 136 (1-18). Publisher's official version : http://doi.org/10.3390/toxins8050136 , Open Access version : http://archimer.ifremer.fr/doc/00333/44429/
Zendong Suzie Zita, Kadiri Medina, Herrenknecht Christine, Nezan Elisabeth, Mazzeo Antonia, Hess Philipp (2016). Algal toxin profiles in Nigerian coastal waters (Gulf of Guinea) using passive sampling and liquid chromatography coupled to mass spectrometry. Toxicon, 114, 16-27. http://doi.org/10.1016/j.toxicon.2016.02.011
Poyer Salome, Loutelier-Bourhis Corinne, Tognetti Vincent, Joubert Laurent, Enche Julien, Bossee Anne, Mondeguer Florence, Hess Philipp, Afonso Carlos (2016). Differentiation of gonyautoxins by ion mobility - mass spectrometry; a cationization study. International Journal Of Mass Spectrometry, 402, 20-28. http://doi.org/10.1016/j.ijms.2016.02.013
Berdalet Elisa, Fleming Lora E., Gowen Richard, Davidson Keith, Hess Philipp, Backer Lorraine C., Moore Stephanie K., Hoagland Porter, Enevoldsen Henrik (2016). Marine harmful algal blooms, human health and wellbeing: challenges and opportunities in the 21st century. Journal Of The Marine Biological Association Of The United Kingdom, 96(1), 61-91. http://doi.org/10.1017/S0025315415001733
Reveillon Damien, Sechet Veronique, Hess Philipp, Amzil Zouher (2016). Systematic detection of BMAA (β-N-methylamino-L-alanine) and DAB (2,4-diaminobutyric acid) in mollusks collected in shellfish production areas along the French coasts. Toxicon, 110, 35-46. http://doi.org/10.1016/j.toxicon.2015.11.011

2015

Kilcoyne Jane, Mccarron Pearse, Hess Philipp, Miles Christopher O. (2015). Effects of Heating on Proportions of Azaspiracids 1–10 in Mussels ( Mytilus edulis ) and Identification of Carboxylated Precursors for Azaspiracids 5, 10, 13, and 15. Journal Of Agricultural And Food Chemistry, 63(51), 10980-10987. http://doi.org/10.1021/acs.jafc.5b04609
Mondeguer Florence, Abadie Eric, Herve Fabienne, Bardouil Michele, Sechet Veronique, Raimbault Virginie, Berteaux Tom, Zendong Suzie Zita, Palvadeau Hubert, Amzil Zouher, Hess Philipp, Fessard Valerie, Huguet Antoine, Sosa Silvio, Tubaro Aurelia, Aráoz Rómulo, Molgó Jordi (2015). Pinnatoxines en lien avec l’espèce Vulcanodinium rugosum (II). http://archimer.ifremer.fr/doc/00285/39635/
Zendong Suzie Zita, Mccarron Pearse, Herrenknecht Christine, Sibat Manoella, Amzil Zouher, Cole Richard B., Hess Philipp (2015). High resolution mass spectrometry for quantitative analysis and untargeted screening of algal toxins in mussels and passive samplers. Journal Of Chromatography A, 1416, 10-21. Publisher's official version : http://doi.org/10.1016/j.chroma.2015.08.064 , Open Access version : http://archimer.ifremer.fr/doc/00277/38848/
Abadie Eric, Kaci Lamia, Berteaux Tom, Hess Philipp, Sechet Veronique, Masseret Estelle, Rolland Jean-Luc, Laabir Mohamed (2015). Effect of Nitrate, Ammonium and Urea on Growth and Pinnatoxin G Production of Vulcanodinium rugosum. Marine Drugs, 13(9), 5642-5656. Publisher's official version : http://doi.org/10.3390/md13095642 , Open Access version : http://archimer.ifremer.fr/doc/00276/38748/
Reveillon Damien, Abadie Eric, Sechet Veronique, Masseret Estelle, Hess Philipp, Amzil Zouher (2015). β-N-methylamino-l-alanine (BMAA) and isomers: Distribution in different food web compartments of Thau lagoon, French Mediterranean Sea. Marine Environmental Research, 110, 8-18. http://doi.org/10.1016/j.marenvres.2015.07.015
Mondeguer Florence, Guitton Yann, Herve Fabienne, Abadie Eric, Dechamps Lucie, Raimbault Virginie, Berteaux Tom, Bardouil Michele, Zendong Suzie Zita, Palvadeau Hubert, Wilson Johanna, Taggart John B, Sechet Veronique, Amzil Zouher, Hess Philipp (2015). Profilage métabolique et contrôle d’hypothèses à travers des cinétiques d’accumulation ou d’élimination des métabolites secondaires associés à la phycotoxicité de bivalves filtreurs. 9èmes Journées Scientifiques du Réseau Français de Métabolomique et Fluxomique (RMFM). 9-11 juin 2015 , Lille, France.
Kilcoyne Jane, Twiner Michael J., Mccarron Pearse, Crain Sheila, Giddings Sabrina D., Foley Barry, Rise Frode, Hess Philipp, Willdns Alistair L., Miles Christopher O. (2015). Structure Elucidation, Relative LC–MS Response and In Vitro Toxicity of Azaspiracids 7–10 Isolated from Mussels (Mytilus edulis). Journal Of Agricultural And Food Chemistry, 63(20), 5083-5091. http://doi.org/10.1021/acs.jafc.5b01320
Brissard Charline, Herve Fabienne, Sibat Manoella, Sechet Veronique, Hess Philipp, Amzil Zouher, Herrenknecht Christine (2015). Characterization of ovatoxin-h, a new ovatoxin analog, and evaluation of chromatographic columns for ovatoxin analysis and purification. Journal of Chromatography A, 1388, 87-101. Publisher's official version : http://doi.org/10.1016/j.chroma.2015.02.015 , Open Access version : http://archimer.ifremer.fr/doc/00252/36302/
Mccarron Pearse, Giddings Sabrina D., Reeves Kelley L., Hess Philipp, Quilliam Michael A. (2015). A mussel (Mytilus edulis) tissue certified reference material for the marine biotoxins azaspiracids. Analytical And Bioanalytical Chemistry, 407(11), 2985-2996. http://doi.org/10.1007/s00216-014-8250-5
Hess Philipp, Geiger Marie, Brochard Solene, Lepretre Thomas, Fessard Valerie, Antignac Jean-Philippe, Dupont Jacques, Sechet Veronique, Vanel Faustine, Mondeguer Florence, Herve Fabienne, Leborgne Sabrina, Deslanglois Gwenaelle, Marshall Lindsey, Rounds Lucy, Guitton Yann, Amzil Zouher, Grovel Olivier, Ruiz Nicolas, Pouchus Francois (2015). COLNACOQ. Composés lipophiles naturels dans l’environnement des coquillages. Rapport final. http://archimer.ifremer.fr/doc/00253/36470/
Poyer Salome, Loutelier-Bourhis Corinne, Coadou Gael, Mondeguer Florence, Enche Julien, Bossee Anne, Hess Philipp, Afonso Carlos (2015). Identification and separation of saxitoxins using hydrophilic interaction liquid chromatography coupled to traveling wave ion mobility-mass spectrometry. Journal Of Mass Spectrometry, 50(1), 175-181. http://doi.org/10.1002/jms.3515
Hess Philipp, Twiner Michael J, Kilcoyne Jane, Sosa Sylvio (2015). Azaspiracid Toxins: Toxicological Profile. In Marine and Freshwater Toxins : Marine and Freshwater Toxins. 2015. Editors: P. Gopalakrishnakone, Vidal Haddad Jr., William R. Kem, Aurelia Tubaro, Euikyung Kim ISBN: 978-94-007-6650-1 (Online) DOI 10.1007/978-94-007-6650-1_20-1 pp.1-19 (Springer Science + Business Media).

2014

Fan Lin, Sun Geng, Qiu Jiangbing, Ma Qimin, Hess Philipp, Li Aifeng (2014). Effect of seawater salinity on pore-size distribution on a poly(styrene)-based HP20 resin and its adsorption of diarrhetic shellfish toxins. Journal Of Chromatography A, 1373, 1-8. Publisher's official version : http://doi.org/10.1016/j.chroma.2014.11.008 , Open Access version : http://archimer.ifremer.fr/doc/00226/33766/
Zendong Zita, Herrenknecht Christine, Abadie Eric, Brissard Charline, Tixier Celine, Mondeguer Florence, Sechet Veronique, Amzil Zouher, Hess Philipp (2014). Extended evaluation of polymeric and lipophilic sorbents for passive sampling of marine toxins. Toxicon, 91, 57-68. Publisher's official version : http://doi.org/10.1016/j.toxicon.2014.03.010 , Open Access version : http://archimer.ifremer.fr/doc/00186/29756/
Reveillon Damien, Abadie Eric, Sechet Veronique, Brient Luc, Savar Veronique, Bardouil Michele, Hess Philipp, Amzil Zouher (2014). Beta-N-Methylamino-L-Alanine: LC-MS/MS Optimization, Screening of Cyanobacterial Strains and Occurrence in Shellfish from Thau, a French Mediterranean Lagoon. Marine Drugs, 12(11), 5441-5467. Publisher's official version : http://doi.org/10.3390/md12115441 , Open Access version : http://archimer.ifremer.fr/doc/00245/35579/
Kilcoyne Jane, Nulty Ciara, Jauffrais Thierry, Mccarron Pearse, Herve Fabienne, Foley Barry, Rise Frode, Crain Sheila, Wilkins Alistair L., Twiner Michael J., Hess Philipp, Miles Christopher O. (2014). Isolation, Structure Elucidation, Relative LC-MS Response, and in Vitro Toxicity of Azaspiracids from the Dinoflagellate Azadinium spinosum. Journal Of Natural Products, 77(11), 2465-2474. http://doi.org/10.1021/np500555k
Fleming L. E., Mcdonough N., Austen M., Mee L., Moore Michelle, Hess Philipp, Depledge M. H., White M., Philippart Katja, Bradbrook P., Smalley A. (2014). Oceans and Human Health: A Rising Tide of Challenges and Opportunities for Europe. Marine Environmental Research, 99, 16-19. Publisher's official version : http://doi.org/10.1016/j.marenvres.2014.05.010 , Open Access version : http://archimer.ifremer.fr/doc/00192/30328/
Brissard Charline, Herrenknecht Christine, Sechet Veronique, Herve Fabienne, Pisapia Francesco, Harcouet Jocelyn, Lemee Rodolphe, Chomerat Nicolas, Hess Philipp, Amzil Zouher (2014). Complex Toxin Profile of French Mediterranean Ostreopsis cf. ovata Strains, Seafood Accumulation and Ovatoxins Prepurification. Marine Drugs, 12(5), 2851-2876. Publisher's official version : http://doi.org/10.3390/md12052851 , Open Access version : http://archimer.ifremer.fr/doc/00199/31025/
Jauffrais Thierry, Sechet Veronique, Truquet Philippe, Amzil Zouher, Herrenknecht Christine, Hess Philipp (2014). Effect of Dilution Rate on Azadinium spinosum and Azaspiracid (AZA) Production in Pilot Scale Photobioreactors for the Harvest of AZA1 and -2. In Molluscan Shellfish Safety : Proceedings of the 8th ICMSS, Charlottetown, PEI, Canada, June 12–17, 2011. Gilbert Sauvé (Ed.). ISBN: 978-94-007-6587-0. Chap.17, pp.197-204 (Springer Netherlands).
Kilcoyne Jane, Jauffrais Thierry, Twiner Michael J., Doucette Gregory J., Aasen Bunaes John A, Sosa Sylvio, Krock Bernd, Sechet Veronique, Nulty Ciara, Salas Rafael, Clarke Dave, Geraghty Jennifer, Duffy Conor, Foley Barry, John Uwe, Quiliam Michael A, Mccarron Pearse, Miles Christopher O., Silke Joe, Cembella Allan, Tilmann Urban, Hess Philipp (2014). AZASPIRACIDS – Toxicological Evaluation, Test Methods and Identifcation of the Source Organisms (ASTOX II).

2013

Hess Philipp, Abadie Eric, Herve Fabienne, Berteaux Tom, Sechet Veronique, Araoz Romulo, Molgo Jordi, Zakarian Armen, Sibat Manoella, Rundberget Thomas, Miles Christopher O., Amzil Zouher (2013). Pinnatoxin G is responsible for atypical toxicity in mussels (Mytilus galloprovincialis) and clams (Venerupis decussata) from Ingril, a French Mediterranean lagoon. Toxicon, 75, 16-26. http://doi.org/10.1016/j.toxicon.2013.05.001
Geiger Marie, Guitton Yann, Vansteelandt M., Kerzaon I., Blanchet Estelle, Du Pont T. Robiou, Frisvad J. C., Hess Philipp, Pouchus Y. F., Grovel Olivier (2013). Cytotoxicity and mycotoxin production of shellfish-derived Penicillium spp., a risk for shellfish consumers. Letters In Applied Microbiology, 57(5), 385-392. http://doi.org/10.1111/lam.12143
Geiger Marie, Desanglois Gwenaelle, Hogeveen Kevin, Fessard Valerie, Lepretre Thomas, Mondeguer Florence, Guitton Yann, Herve Fabienne, Sechet Veronique, Grovel Olivier, Pouchus Yves-Francois, Hess Philipp (2013). Cytotoxicity, Fractionation and Dereplication of Extracts of the Dinoflagellate Vulcanodinium rugosum, a Producer of Pinnatoxin G. Marine Drugs, 11(9), 3350-3371. Publisher's official version : http://doi.org/10.3390/md11093350 , Open Access version : http://archimer.ifremer.fr/doc/00156/26723/
Jauffrais Thierry, Sechet Veronique, Herrenknecht Christine, Truquet Philippe, Savar Veronique, Tillmann Urban, Hess Philipp (2013). Effect of environmental and nutritional factors on growth and azaspiracid production of the dinoflagellate Azadinium spinosum. Harmful Algae, 27, 138-148. http://doi.org/10.1016/j.hal.2013.05.009
Hess Philipp, Mondeguer Florence, Glauner Thomas, Wust Bernard, Sibat Manoella, Zendong Suzie Zita, Herrenknecht Christine, Sechet Veronique (2013). Metabolomic Analysis of Marine Microalgae Using High Resolution Mass Spectrometry for Taxonomic Comparisons and Screening of Marine Biotoxins. ASMS 2013 - 61st American Society for Mass Spectrometry (ASMS) - Minneapolis (USA) , June 9-13, 2013. http://archimer.ifremer.fr/doc/00179/29037/
Mondeguer Florence, Antignac Jean-Philippe, Guitton Yann, Monteau Fabrice, Le Borgne Sabrina, Hess Philipp (2013). Stratégie de mesure non ciblée de type métabolomique (couplage LC-HRMS ) pour identifier différents groupes de composés bioactifs accumulés dans les mollusques bivalves. 6e Journées Scientifiques du Réseau Français Métabolomique et Fluxomique (RFMF) : Echanger, partager au sein de la communauté d'acteurs de la métabolomique et de la fluxomique - 21-23 mai 2012, Nantes. http://archimer.ifremer.fr/doc/00179/29042/
Poyer Salome, Loutelier-Bourhis Corinne, Mondeguer Florence, Coadou Gael, Hubert-Roux Marie, Enche Julien, Bossee Anne, Hess Philipp, Afonso Carlos (2013). Identification of paralytic shellfish poisons using liquid chromatography / ion mobility - high resolution mass spectrometry. EuPA conference (EUropean Proteome Association) - Saint Malo (FRANCE), October 14-17, 2013. http://archimer.ifremer.fr/doc/00179/29039/
Moore Michael N., Depledge Michael H., Fleming Lora, Hess Philipp, Lees David, Leonard Paul, Madsen Lise, Owen Richard, Pirlet Hans, Seys Jan, Vasconcelos Vitor, Viarengo Aldo (2013). Oceans and Human Health (OHH): a European Perspective from the Marine Board of the European Science Foundation (Marine Board-ESF). Microbial Ecology, 65(4), 889-900. http://doi.org/10.1007/s00248-013-0204-5
Jauffrais Thierry, Kilcoyne Jane, Herrenknecht Christine, Truquet Philippe, Sechet Veronique, Miles Christopher O., Hess Philipp (2013). Dissolved azaspiracids are absorbed and metabolized by blue mussels (Mytilus edulis). Toxicon, 65, 81-89. http://doi.org/10.1016/j.toxicon.2013.01.010
Zendong Suzie Zita, Herrenknecht Christine, Mondeguer Florence, Hess Philipp (2013). Metabolomic approach for the analysis of micro-algae : direct analysis versus passive sampling. 4th International Symposium On Marine & Freshwater Toxin Analysis and AOAC Task Force Meeting, 5-9 May 2013, Baiona, Spain. http://archimer.ifremer.fr/doc/00179/29040/

2012

Jauffrais Thierry, Contreras Andrea, Herrenknecht Christine, Truquet Philippe, Sechet Veronique, Tillmann Urban, Hess Philipp (2012). Effect of Azadinium spinosum on the feeding behaviour and azaspiracid accumulation of Mytilus edulis. Aquatic Toxicology, 124, 179-187. Publisher's official version : http://doi.org/10.1016/j.aquatox.2012.08.016 , Open Access version : http://archimer.ifremer.fr/doc/00090/20174/
Aune Tore, Espenes Arild, Aasen John A. Bunaes, Quilliam Michael A., Hess Philipp, Larsen Stig (2012). Study of possible combined toxic effects of azaspiracid-1 and okadaic acid in mice via the oral route. Toxicon, 60(5), 895-906. http://doi.org/10.1016/j.toxicon.2012.06.007
Hess Philipp, Goulletquer Philippe (2012). Toxic Microalgae – Algal toxins. Know and emerging threats to seafood consumers and the marine environment. Key environmental issues for marine coastal ecosystems, 5th Sino-French SEED Seminar, October 2nd & 3rd 2012, Montpellier.
Hess Philipp, Herve Fabienne, Abadie Eric, Sechet Veronique, Molgo Jordi, Amzil Zouher, Fessard Valerie (2012). Pinnatoxines en lien avec l’espèce Vulcanodinium rugosum. http://archimer.ifremer.fr/doc/00094/20518/
Jauffrais Thierry, Marcaillou-Le Baut Claire, Herrenknecht Christine, Truquet Philippe, Sechet Veronique, Nicolau Elodie, Tillmann Urban, Hess Philipp (2012). Azaspiracid accumulation, detoxification and biotransformation in blue mussels (Mytilus edulis) experimentally fed Azadinium spinosum. Toxicon, 60(4), 582-595. http://doi.org/10.1016/j.toxicon.2012.04.351
Hess Philipp, Bavouzet Gerard (2012). Information sur les intoxications potentielles dues à la consommation d'organismes marins autres que les mollusques bivalves en juillet 2012. Capitainerie du Port de Plaisance de Lorient (Morbihan-56), Ref. STALO/E12_084, 2p.
Jauffrais Thierry, Kilcoyne Jane, Sechet Veronique, Herrenknecht Christine, Truquet Philippe, Herve Fabienne, Berard Jean-Baptiste, Nulty Ciara, Taylor Sarah, Tillmann Urban, Miles Christopher O., Hess Philipp (2012). Production and Isolation of Azaspiracid-1 and -2 from Azadinium spinosum Culture in Pilot Scale Photobioreactors. Marine Drugs, 10(6), 1360-1382. Publisher's official version : http://doi.org/10.3390/md10061360 , Open Access version : http://archimer.ifremer.fr/doc/00088/19875/
Jauffrais Thierry, Herrenknecht Christine, Sechet Veronique, Sibat Manoella, Tillmann Urban, Krock Bernd, Kilcoyne Jane, Miles Christopher O., Mccarron Pearse, Amzil Zouher, Hess Philipp (2012). Quantitative analysis of azaspiracids in Azadinium spinosum cultures. Analytical And Bioanalytical Chemistry, 403(3), 833-846. http://doi.org/10.1007/s00216-012-5849-2
Kilcoyne Jane, Keogh Adela, Clancy Ger, Leblanc Patricia, Burton Ian, Quilliam Michael A., Hess Philipp, Miles Christopher O. (2012). Improved Isolation Procedure for Azaspiracids from Shellfish, Structural Elucidation of Azaspiracid-6, and Stability Studies. Journal Of Agricultural And Food Chemistry, 60(10), 2447-2455. http://doi.org/10.1021/jf2048788
Mondeguer Florence, Antignac Jean-Philippe, Guitton Yann, Monteau Fabrice, Le Borgne Sabrina, Hess Philipp (2012). Nouvelle stratégie de caractérisation non ciblée de type métabolomique au service de l’identification de composés bioactifs accumulés dans les mollusques bivalves. Spectra Analyse, (284), 24-33. Open Access version : http://archimer.ifremer.fr/doc/00077/18784/

2011

Salas Rafael, Tillmann Urban, John Uwe, Kilcoyne Jane, Burson Amanda, Cantwell Caoimhe, Hess Philipp, Jauffrais Thierry, Silke Joe (2011). The role of Azadinium spinosum (Dinophyceae) in the production of azaspiracid shellfish poisoning in mussels. Harmful Algae, 10(6), 774-783. http://doi.org/10.1016/j.hal.2011.06.010
Aasen John A. B., Espenes Arild, Miles Christopher O., Samdal Ingunn A., Hess Philipp, Aune Tore (2011). Combined oral toxicity of azaspiracid-1 and yessotoxin in female NMRI mice. Toxicon, 57(6), 909-917. http://doi.org/10.1016/j.toxicon.2011.03.014
Mccarron Pearse, Emteborg Hakan, Nulty Ciara, Rundberget Thomas, Loader Jared I., Teipel Katharina, Miles Christopher O., Quilliam Michael A., Hess Philipp (2011). A mussel tissue certified reference material for multiple phycotoxins. Part 1: design and preparation. Analytical And Bioanalytical Chemistry, 400(3), 821-833. http://doi.org/10.1007/s00216-011-4786-9
Tong Mengmeng, Kulis David M., Fux Elie, Smith Juliette L., Hess Philipp, Zhou Qixing, Anderson Donald M. (2011). The effects of growth phase and light intensity on toxin production by Dinophysis acuminata from the northeastern United States. Harmful Algae, 10(3), 254-264. http://doi.org/10.1016/j.hal.2010.10.005
Lawrence Jim, Loreal Henri, Toyofuku Hajime, Hess Philipp, Iddya Karunasagar (2011). Assessment and management of biotoxin risks in bivalve molluscs. http://archimer.ifremer.fr/doc/00085/19588/

2010

Hess Philipp, Nicolau Elodie (2010). Recent developments in the detection of phycotoxins. 18èmes Rencontres en Toxinologie - Société Française pour l’Etude des Toxines (SFET); 13 - 14 décembre 2010, Institut Pasteur Paris.
Fux Elie, Gonzalez-Gil Sonsoles, Lunven Michel, Gentien Patrick, Hess Philipp (2010). Production of diarrhetic shellfish poisoning toxins and pectenotoxins at depths within and below the euphotic zone. Toxicon, 56(8), 1487-1496. http://doi.org/10.1016/j.toxicon.2010.09.007
Aasen John A. B., Espenes Arild, Hess Philipp, Aune Tore (2010). Sub-lethal dosing of azaspiracid-1 in female NMRI mice. Toxicon, 56(8), 1419-1425. http://doi.org/10.1016/j.toxicon.2010.08.007
Perez Ruth A, Rehmann Nils, Crain Sheila, Leblanc Patricia, Craft Cheryl, Mackinnon Shawna, Reeves Kelley, Burton Ian W., Walter John A., Hess Philipp, Quilliam Michael A., Melanson Jeremy E. (2010). The preparation of certified calibration solutions for azaspiracid-1,-2, and-3, potent marine biotoxins found in shellfish. Analytical And Bioanalytical Chemistry, 398(5), 2243-2252. http://doi.org/10.1007/s00216-010-4161-2
Hess Philipp (2010). Contributions to the characterisation of risks posed by marine biotoxins. HDR. http://archimer.ifremer.fr/doc/00015/12661/
Hess Philipp (2010). Requirements for screening and confirmatory methods for the detection and quantification of marine biotoxins in end-product and official control. Analytical And Bioanalytical Chemistry, 397(5), 1683-1694. http://doi.org/10.1007/s00216-009-3444-y
Gaignon Jean-Louis, Ryckaert Mireille, Hess Philipp, Nezan Elisabeth, Chomerat Nicolas (2010). Opportunité d'autoriser le transfert de juvéniles d'huîtres creuses au départ du littoral du département de Charente-Maritime. DDTM Charente Maritime, Direction Départementale des Territoires et de la Mer, La Rochelle 17, Ref. D/CN - 2010.67, 1p.
Rossini Gian Paolo, Hess Philipp (2010). Phycotoxins: chemistry, mechanisms of action and shellfish poisoning. In Molecular, clinical and environmental toxicology : Volume 2. Clinical toxicology (Birkhauser Boston).
Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Emerging toxins: Ciguatoxin group. European Commission, Ref. EFSA-Q-2009-00955, 38p.
EFSA Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Emerging toxins: Brevetoxin group. European Commission, Ref. EFSA-Q-2006-065I, 29p.
EFSA Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Cyclic imines (spirolides, gymnodimines, pinnatoxins and pteriatoxins). European Commission, Ref. EFSA-Q-2006-065F, 39p.
Jauffrais Thierry, Sechet Veronique, Herrenknecht Christine, Tillmann Urban, Krock Bernd, Amzil Zouher, Hess Philipp (2010). Growth and toxin production of Azadinium spinosum in batch and continuous culture. 14th International Conference on Harmful Algae - ICHA 2010. 1-5 November 2010, Hersonissos, Crete. http://archimer.ifremer.fr/doc/00152/26348/
EFSA Panel on Contaminants in the Food Chain (2010). Statement on further elaboration on consumption figure of 400 g shellfish meat on the basis of new consumption data. European Commission, Ref. EFSA-Q-2010-00155, 20p.

2009

Stewart Linda D., Hess Philipp, Connolly Lisa, Elliott Christopher T. (2009). Development and Single-Laboratory Validation of a Pseudofunctional Biosensor Immunoassay for the Detection of the Okadaic Acid Group of Toxins. Analytical Chemistry, 81(24), 10208-10214. http://doi.org/10.1021/ac902084a
Hackett Jeremiah D., Tong Mengmeng, Kulis David M., Fux Elie, Hess Philipp, Bire Ronel, Anderson Donald M. (2009). DSP toxin production de novo in cultures of Dinophysis acuminata (Dinophyceae) from North America. Harmful Algae, 8(6), 873-879. http://doi.org/10.1016/j.hal.2009.04.004
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Marine Biotoxins in Shellfish - Summary on regulated marine biotoxins. European Commission, Ref. The EFSA Journal (2009) 1306, 1-23, 23p.
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on marine biotoxins in shellfish - domoic acid. European Commission, Ref. The EFSA Journal (2009) 1181, 1-61, 61p.
Hess Philipp, Butter Tim, Petersen Andrew, Silke Joe, Mcmahon Terry (2009). Performance of the EU-harmonised mouse bioassay for lipophilic toxins for the detection of azaspiracids in naturally contaminated mussel (Mytilus edulis) hepatopancreas tissue homogenates characterised by liquid chromatography coupled to tandem mass spectrometry. Toxicon, 53(7-8), 713-722. http://doi.org/10.1016/j.toxicon.2009.02.015
Gerssen Arjen, Mcelhinney Mairead A., Mulder Patrick P. J., Bire Ronel, Hess Philipp, De Boer Jacob (2009). Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry. Analytical And Bioanalytical Chemistry, 394(4), 1213-1226. http://doi.org/10.1007/s00216-009-2790-0
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on marine biotoxins in shellfish - pectenotoxin group. European Commission, Ref. The EFSA Journal (2009) 1109, 1-47, 47p.
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Marine Biotoxins in Shellfish - Saxitoxin Group. European Commission, Ref. The EFSA Journal (2009) 1019, 1-76, 76p.
(2009) Statement of the Panel on Contaminants in the Food Chain on a request from the European Commission on the Influence of processing on the levels of lipophilic marine biotoxins in bivalve molluscs. European Commission, Ref. The EFSA Journal (2009) 1016, 1-10, 10p.
Fux Elie, Bire Ronel, Hess Philipp (2009). Comparative accumulation and composition of lipophilic marine biotoxins in passive samplers and in mussels (M. edulis) on the West Coast of Ireland. Harmful Algae, 8(3), 523-537. http://doi.org/10.1016/j.hal.2008.10.007
Mccarron Pearse, Kilcoyne Jane, Miles Christopher O., Hess Philipp (2009). Formation of Azaspiracids-3,-4,-6, and-9 via Decarboxylation of Carboxyazaspiracid Metabolites from Shellfish. Journal Of Agricultural And Food Chemistry, 57(1), 160-169. http://doi.org/10.1021/jf8025138
(2009) EFSA Panel on Contaminants in the Food Chain (CONTAM); Scientific Opinion on marine biotoxins in shellfish - Palytoxin group. European Commission, Ref. EFSA Journal 2009; 7(12):1393, 38p.

2008

(2008) Opinion of the Scientific Panel on Contaminants in the Food chain on a request from the European Commission on marine biotoxins in shellfish - yessotoxin group. European Commission, Ref. The EFSA Journal (2008) Journal number, 907, 1-62, 62p.
Alfonso Carmen, Rehmann Nils, Hess Philipp, Alfonso Amparo, Wandscheer Carolina B., Abuin Maria, Vale Carmen, Otero Paz, Vieytes Mercedes R., Botana Luis M. (2008). Evaluation of Various pH and Temperature Conditions on the Stability of Azaspiracids and Their Importance in Preparative Isolation and Toxicological Studies. Analytical Chemistry, 80(24), 9672-9680. http://doi.org/10.1021/ac801506d
Fux E, Marcaillou-Le Baut Claire, Mondeguer Florence, Bire R, Hess Philipp (2008). Field and mesocosm trials on passive sampling for the study of adsorption and desorption behaviour of lipophilic toxins with a focus on OA and DTX1. Harmful Algae, 7(5), 574-583. Publisher's official version : http://doi.org/10.1016/j.hal.2007.12.008 , Open Access version : http://archimer.ifremer.fr/doc/00000/4739/
Vale Paulo, Bire Ronel, Hess Philipp (2008). Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast. Toxicon, 51(8), 1449-1456. http://doi.org/10.1016/j.toxicon.2008.03.022
Twiner Michael J., Rehmann Nils, Hess Philipp, Doucette Gregory J. (2008). Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts. Marine Drugs, 6(2), 39-72. Publisher's official version : http://doi.org/10.3390/md20080004 , Open Access version : http://archimer.ifremer.fr/doc/00077/18805/
Mccarron Pearse, Kilcoyne Jane, Hess Philipp (2008). Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels (Mytilus edulis). Toxicon, 51(6), 1081-1089. http://doi.org/10.1016/j.toxicon.2008.01.009
Twiner Michael J., Ryan James C., Morey Jeanine S., Smith Kent J., Hammad Samar M., Van Dolah Frances M., Hess Philipp, Mcmahon Terry, Satake Masayuki, Yasumoto Takeshi, Doucette Gregory J. (2008). Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Genomics, 91(3), 289-300. http://doi.org/10.1016/j.ygeno.2007.10.015
Fux E., Rode D., Bire R., Hess Philipp (2008). Approaches to the evaluation of matrix effects in the liquid chromatography-mass spectrometry (LC-MS) analysis of three regulated lipophilic toxin groups in mussel matrix (Mytilus edulis). Food Additives And Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment, 25(8), 1024-1032. http://doi.org/10.1080/02652030802008601
Rehmann Nils, Hess Philipp, Quilliam Michael A. (2008). Discovery of new analogs of the marine biotoxin azaspiracid in blue mussels (Mytilus edulis) by ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Communications In Mass Spectrometry, 22(4), 549-558. http://doi.org/10.1002/rcm.3385

2007

Fux Elie, Mcmillan Daniel, Bire Ronel, Hess Philipp (2007). Development of an ultra-performance liquid chromatography-mass spectrometry method for the detection of lipophilic marine toxins. Journal Of Chromatography A, 1157(1-2), 273-280. http://doi.org/10.1016/j.chroma.2007.05.016
Larsen Kristofer, Petersen Dirk, Wilkins Alistair L., Samdal Ingunn A., Sandvik Morten, Rundberget Thomas, Goldstone David, Arcus Vickery, Hovgaard Peter, Rise Frode, Rehmann Nils, Hess Philipp, Miles Christopher O. (2007). Clarification of the C-35 stereochemistries of dinophysistoxin-1 and dinophysistoxin-2 and its consequences for binding to protein phosphatase. Chemical Research In Toxicology, 20(6), 868-875. http://doi.org/10.1021/tx700016m
Mccarron Pearse, Kotterman Michiel, De Boer Jacob, Rehmann Nils, Hess Philipp (2007). Feasibility of gamma irradiation as a stabilisation technique in the preparation of tissue reference materials for a range of shellfish toxins. Analytical And Bioanalytical Chemistry, 387(7), 2487-2493. http://doi.org/10.1007/s00216-006-0935-y
Mccarron Pearse, Burrell Stephen, Hess Philipp (2007). Effect of addition of antibiotics and an antioxidant on the stability of tissue reference materials for domoic acid, the amnesic shellfish poison. Analytical And Bioanalytical Chemistry, 387(7), 2495-2502. http://doi.org/10.1007/s00216-006-0833-3
Hess Philipp, Mccarron Pearse, Quilliam Michael A. (2007). Fit-for-purpose shellfish reference materials for internal and external quality control in the analysis of phycotoxins. Analytical And Bioanalytical Chemistry, 387(7), 2463-2474. http://doi.org/10.1007/s00216-006-0792-8
Mccarron Pearse, Emteborg Hakan, Hess Philipp (2007). Freeze-drying for the stabilisation of shellfish toxins in mussel tissue (Mytilus edulis) reference materials. Analytical And Bioanalytical Chemistry, 387(7), 2475-2486. http://doi.org/10.1007/s00216-006-1104-z
Ronzitti Giuseppe, Hess Philipp, Rehmann Nils, Rossini Gian Paolo (2007). Azaspiracid-1 alters the E-cadherin pool in epithelial cells. Toxicological Sciences, 95(2), 427-435. http://doi.org/10.1093/toxsci/kfl167
Bogan Y. M., Bender K., Hervas A., Kennedy D. J., Slater J. W., Hess Philipp (2007). Spatial variability of domoic acid concentration in king scallops Pecten maximus off the southeast coast of Ireland. Harmful Algae, 6(1), 1-14. http://doi.org/10.1016/j.hal.2006.05.004
Bogan Y. M., Harkin A. L., Gillespie J., Kennedy D. J., Hess Philipp, Slater J. W. (2007). The influence of size on domoic acid concentration in king scallop, Pecten maximus (L.). Harmful Algae, 6(1), 15-28. http://doi.org/10.1016/j.hal.2006.05.005
Bogan Y. M., Kennedy D. J., Harkin A. L., Gillespie J., Vause B. J., Beukers-Stewart B. D., Hess Philipp, Slater J. W. (2007). Variation in domoic acid concentration in king scallop (Pecten maximus) from fishing grounds around the Isle of Man. Harmful Algae, 6(1), 81-92. http://doi.org/10.1016/j.hal.2006.07.002
Aune Tore, Larsen Stig, Aasen John A. B., Rehmann Nils, Satake Masayuki, Hess Philipp (2007). Relative toxicity of dinophysistoxin-2 (DTX-2) compared with okadaic acid, based on acute intraperitoneal toxicity in mice. Toxicon, 49(1), 1-7. http://doi.org/10.1016/j.toxicon.2006.07.033

2006

Wilkins Alistair L., Rehmann Nils, Torgersen Trine, Rundberget Thomas, Keogh Myra, Petersen Dirk, Hess Philipp, Rise Frode, Miles Christopher O. (2006). Identification of fatty acid esters of pectenotoxin-2 seco acid in blue mussels (Mytilus edulis) from Ireland. Journal Of Agricultural And Food Chemistry, 54(15), 5672-5678. http://doi.org/10.1021/jf060396j
Kulagina Nv, Twiner Mj, Hess Philipp, Mcmahon T, Satake M, Yasumoto T, Ramsdell Js, Doucette Gj, Ma W, O'Shaughnessy Tj (2006). Azaspiracid-1 inhibits bioelectrical activity of spinal cord neuronal networks. Toxicon, 47(7), 766-773. http://doi.org/10.1016/j.toxicon.2006.02.011
Hess Philipp, Grune Barbara, Anderson David B., Aune Tore, Botana Luis M., Caricato Paolo, Van Egmond Hans P., Halder Marlies, Hall Sherwood, Lawrence James F., Moffat Colin, Poletti Roberto, Richmond John, Rossini Gian Paolo, Seamer Catherine, Vilageliu Jorge Serratosa (2006). Three Rs approaches in marine biotoxin testing - The report and recommendations of a joint ECVAM/DG SANCO workshop (ECVAM workshop 55). Atla-alternatives To Laboratory Animals, 34(2), 193-224.
Bogan Ym, Kennedy D, Harkin Al, Gillespie J, Hess Philipp, Slater Jw (2006). Comparison of domoic acid concentration in king scallops, Pecten maximus from seabed and suspended culture systems. Journal Of Shellfish Research, 25(1), 129-135. http://doi.org/10.2983/0730-8000(2006)25[129:CODACI]2.0.CO;2
Mccarron P, Hess Philipp (2006). Tissue distribution and effects of heat treatments on the content of domoic acid in blue mussels, Mytilus edulis. Toxicon, 47(4), 473-479. http://doi.org/10.1016/j.toxicon.2006.01.004

2005

Dell'Aversano C, Hess Philipp, Quilliam Ma (2005). Hydrophilic interaction liquid chromatography-mass spectrometry for the analysis of paralytic shellfish poisoning (PSP) toxins. Journal Of Chromatography A, 1081(2), 190-201. http://doi.org/10.1016/j.chroma.2005.05.056
Hess Philipp, Nguyen L, Aasen J, Keogh M, Kilcoyne J, Mccarron P, Aune T (2005). Tissue distribution, effects of cooking and parameters affecting the extraction of azaspiracids from mussels, Mytilus edulis, prior to analysis by liquid chromatography coupled to mass spectrometry. Toxicon, 46(1), 62-71. http://doi.org/10.1016/j.toxicon.2005.03.010
Colman Jr, Twiner Mj, Hess Philipp, Mcmahon T, Satake M, Yasumoto T, Doucette Gj, Ramsdell Js (2005). Teratogenic effects of azaspiracid-1 identified by microinjection of Japanese medaka (Oryzias latipes) embryos. Toxicon, 45(7), 881-890. http://doi.org/10.1016/j.toxicon.2005.02.014
Twiner Mj, Hess Philipp, Dechraoui Myb, Mcmahon T, Samons Ms, Satake M, Yasumoto T, Ramsdell Js, Doucette Gj (2005). Cytotoxic and cytoskeletal effects of azaspiracid-1 on mammalian cell lines. Toxicon, 45(7), 891-900. http://doi.org/10.1016/j.toxicon.2005.02.015
Hess Philipp, Morris S, Stobo La, Brown Na, Mcevoy Jdg, Kennedy G, Young Pb, Slattery D, Mcgovern E, Mcmahon T, Gallacher S (2005). LC-UV and LC-MS methods for the determination of domoic acid. Trac-trends In Analytical Chemistry, 24(4), 358-367. http://doi.org/10.1016/j.trac.2004.11.019

2001

Jaime E, Hummert C, Hess Philipp, Luckas B (2001). Determination of paralytic shellfish poisoning toxins by high-performance ion-exchange chromatography. Journal Of Chromatography A, 929(1-2), 43-49. http://doi.org/10.1016/S0021-9673(01)01181-5
Hess Philipp, Gallacher S, Bates La, Brown N, Quilliam Ma (2001). Determination and confirmation of the amnesic shellfish poisoning toxin, domoic acid, in shellfish from Scotland by liquid chromatography and mass spectrometry. Journal Of Aoac International, 84(5), 1657-1667.
Campbell Da, Kelly Ms, Busman M, Bolch Cj, Wiggins E, Moeller Pdr, Morton Sl, Hess Philipp, Shumway Se (2001). Amnesic shellfish poisoning in the king scallop, Pecten maximus, from the west coast of Scotland. Journal Of Shellfish Research, 20(1), 75-84.
Hess Philipp, Wells De (2001). Evaluation of dialysis as a technique for the removal of lipids prior to the GC determination of ortho- and non-ortho-chlorobiphenyls, using C-14-labelled congeners. Analyst, 126(6), 829-834. http://doi.org/10.1039/b101460i

1995

Hess Philipp, Deboer J, Cofino Wp, Leonards Peg, Wells De (1995). Critical review of the analysis of non- and mono-ortho-chlorobiphenyls. Journal Of Chromatography A, 703(1-2), 417-465. http://doi.org/10.1016/0021-9673(95)00298-2


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