Philipp Hess
Directeur de l'unité de recherche EMP
Unité Environnement, Microbiologie et Phycotoxines
Tél : 02 40 37 42 57
Fax : 02 40 37 40 26
Adresse postale : Ifremer - Centre Atlantique - Rue de l'Ile d'Yeu - BP 21105 - 44311 NANTES Cedex 03
Fonctions actuelles
Directeur de l'Unité de Recherche Ifremer Environnement, Microbiologie et Phycotoxines (EMP)
Responsable du projet Ifremer Risques Chimiques Sanitaires Associés Aux Produits de la Mer (RISCAP)
Directeur Adjoint de l' Institut Universitaire Mer et Littoral - IUML (FR 3473 CNRS / Université de Nantes / Ifremer)
Bibliographie
2012
Jauffrais Thierry, Herrenknecht Christine, Sechet Veronique, Sibat Manoella, Tillmann Urban, Krock Bernd, Kilcoyne Jane, Miles Christopher O., Mccarron Pearse, Amzil Zouher, Hess Philipp (2012). Quantitative analysis of azaspiracids in Azadinium spinosum cultures. Analytical and Bioanalytical Chemistry, 403, 833-846. Publisher's official version : http://dx.doi.org/10.1007/s00216-012-5849-2 , Open Access version : http://archimer.ifremer.fr/doc/00077/18812/
Kilcoyne Jane, Keogh Adela, Clancy Ger, Leblanc Patricia, Burton Ian, Quilliam Michael A., Hess Philipp, Miles Christopher O. (2012). Improved Isolation Procedure for Azaspiracids from Shellfish, Structural Elucidation of Azaspiracid-6, and Stability Studies. Journal Of Agricultural And Food Chemistry, 60(10), 2447-2455. http://dx.doi.org/10.1021/jf2048788
Mondeguer Florence, Antignac Jean-Philippe, Guitton Yann, Monteau Fabrice, Le Borgne Sabrina, Hess Philipp (2012). Nouvelle stratégie de caractérisation non ciblée de type métabolomique au service de l’identification de composés bioactifs accumulés dans les mollusques bivalves. Spectra Analyse, (284), 24-33.
2011
Salas Rafael, Tillmann Urban, John Uwe, Kilcoyne Jane, Burson Amanda, Cantwell Caoimhe, Hess Philipp, Jauffrais Thierry, Silke Joe (2011). The role of Azadinium spinosum (Dinophyceae) in the production of azaspiracid shellfish poisoning in mussels. Harmful Algae, 10(6), 774-783. Publisher's official version : http://dx.doi.org/10.1016/j.hal.2011.06.010 , Open Access version : http://archimer.ifremer.fr/doc/00049/16049/
Aasen John A. B., Espenes Arild, Miles Christopher O., Samdal Ingunn A., Hess Philipp, Aune Tore (2011). Combined oral toxicity of azaspiracid-1 and yessotoxin in female NMRI mice. Toxicon, 57(6), 909-917. Publisher's official version : http://dx.doi.org/10.1016/j.toxicon.2011.03.014 , Open Access version : http://archimer.ifremer.fr/doc/00034/14477/
Mccarron Pearse, Emteborg Hakan, Nulty Ciara, Rundberget Thomas, Loader Jared I., Teipel Katharina, Miles Christopher O., Quilliam Michael A., Hess Philipp (2011). A mussel tissue certified reference material for multiple phycotoxins. Part 1: design and preparation. Analytical And Bioanalytical Chemistry, 400(3), 821-833. Publisher's official version : http://dx.doi.org/10.1007/s00216-011-4786-9 , Open Access version : http://archimer.ifremer.fr/doc/00037/14826/
Tong Mengmeng, Kulis David M., Fux Elie, Smith Juliette L., Hess Philipp, Zhou Qixing, Anderson Donald M. (2011). The effects of growth phase and light intensity on toxin production by Dinophysis acuminata from the northeastern United States. Harmful Algae, 10(3), 254-264. Publisher's official version : http://dx.doi.org/10.1016/j.hal.2010.10.005 , Open Access version : http://archimer.ifremer.fr/doc/00037/14827/
2010
Hess Philipp, Nicolau Elodie (2010). Recent developments in the detection of phycotoxins. 18èmes Rencontres en Toxinologie - Société Française pour l’Etude des Toxines (SFET); 13 - 14 décembre 2010, Institut Pasteur Paris. http://archimer.ifremer.fr/doc/00019/12975/
Aasen John A. B., Espenes Arild, Hess Philipp, Aune Tore (2010). Sub-lethal dosing of azaspiracid-1 in female NMRI mice. Toxicon, 56(8), 1419-1425. http://dx.doi.org/10.1016/j.toxicon.2010.08.007
Fux Elie, Gonzalez-Gil Sonsoles, Lunven Michel, Gentien Patrick, Hess Philipp (2010). Production of diarrhetic shellfish poisoning toxins and pectenotoxins at depths within and below the euphotic zone. Toxicon, 56(8), 1487-1496. http://dx.doi.org/10.1016/j.toxicon.2010.09.007
Perez Ruth A, Rehmann Nils, Crain Sheila, Leblanc Patricia, Craft Cheryl, Mackinnon Shawna, Reeves Kelley, Burton Ian W., Walter John A., Hess Philipp, Quilliam Michael A., Melanson Jeremy E. (2010). The preparation of certified calibration solutions for azaspiracid-1,-2, and-3, potent marine biotoxins found in shellfish. Analytical And Bioanalytical Chemistry, 398(5), 2243-2252. http://dx.doi.org/10.1007/s00216-010-4161-2
Hess Philipp (2010). Contributions to the characterisation of risks posed by marine biotoxins. HDR. http://archimer.ifremer.fr/doc/00015/12661/
Hess Philipp (2010). Requirements for screening and confirmatory methods for the detection and quantification of marine biotoxins in end-product and official control. Analytical And Bioanalytical Chemistry, 397(5), 1683-1694. Publisher's official version : http://dx.doi.org/10.1007/s00216-009-3444-y , Open Access version : http://archimer.ifremer.fr/doc/00006/11767/
Gaignon Jean-Louis, Ryckaert Mireille, Hess Philipp, Nezan Elisabeth, Chomerat Nicolas (2010). Opportunité d'autoriser le transfert de juvéniles d'huîtres creuses au départ du littoral du département de Charente-Maritime. DDTM Charente Maritime, Direction Départementale des Territoires et de la Mer, La Rochelle 17, Ref. D/CN - 2010.67, 1p., 2p.
EFSA Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Cyclic imines (spirolides, gymnodimines, pinnatoxins and pteriatoxins). European Commission, Ref. EFSA-Q-2006-065F, 39p.
EFSA Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Emerging toxins: Brevetoxin group. European Commission, Ref. EFSA-Q-2006-065I, 29p.
Panel on Contaminants in the Food Chain (2010). Scientific Opinion on marine biotoxins in shellfish - Emerging toxins: Ciguatoxin group. European Commission, Ref. EFSA-Q-2009-00955, 38p.
Rossini Gian Paolo, Hess Philipp (2010). Phycotoxins: chemistry, mechanisms of action and shellfish poisoning. In Molecular, clinical and environmental toxicology : Volume 2. Clinical toxicology (Birkhauser Boston).
EFSA Panel on Contaminants in the Food Chain (2010). Statement on further elaboration on consumption figure of 400 g shellfish meat on the basis of new consumption data. European Commission, Ref. EFSA-Q-2010-00155, 20p.
2009
Stewart Linda D., Hess Philipp, Connolly Lisa, Elliott Christopher T. (2009). Development and Single-Laboratory Validation of a Pseudofunctional Biosensor Immunoassay for the Detection of the Okadaic Acid Group of Toxins. Analytical Chemistry, 81(24), 10208-10214. http://dx.doi.org/10.1021/ac902084a
Hackett Jeremiah D., Tong Mengmeng, Kulis David M., Fux Elie, Hess Philipp, Bire Ronel, Anderson Donald M. (2009). DSP toxin production de novo in cultures of Dinophysis acuminata (Dinophyceae) from North America. Harmful Algae, 8(6), 873-879. http://dx.doi.org/10.1016/j.hal.2009.04.004
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Marine Biotoxins in Shellfish - Summary on regulated marine biotoxins. European Commission, Ref. The EFSA Journal (2009) 1306, 1-23, 23p.
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on marine biotoxins in shellfish - domoic acid. European Commission, Ref. The EFSA Journal (2009) 1181, 1-61, 61p.
Hess Philipp, Butter Tim, Petersen Andrew, Silke Joe, Mcmahon Terry (2009). Performance of the EU-harmonised mouse bioassay for lipophilic toxins for the detection of azaspiracids in naturally contaminated mussel (Mytilus edulis) hepatopancreas tissue homogenates characterised by liquid chromatography coupled to tandem mass spectrometry. Toxicon, 53(7-8), 713-722. http://dx.doi.org/10.1016/j.toxicon.2009.02.015
Gerssen Arjen, Mcelhinney Mairead A., Mulder Patrick P. J., Bire Ronel, Hess Philipp, De Boer Jacob (2009). Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry. Analytical And Bioanalytical Chemistry, 394(4), 1213-1226. http://dx.doi.org/10.1007/s00216-009-2790-0
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on marine biotoxins in shellfish - pectenotoxin group. European Commission, Ref. The EFSA Journal (2009) 1109, 1-47, 47p.
(2009) Scientific Opinion of the Panel on Contaminants in the Food Chain on a request from the European Commission on Marine Biotoxins in Shellfish - Saxitoxin Group. European Commission, Ref. The EFSA Journal (2009) 1019, 1-76, 76p.
(2009) Statement of the Panel on Contaminants in the Food Chain on a request from the European Commission on the Influence of processing on the levels of lipophilic marine biotoxins in bivalve molluscs. European Commission, Ref. The EFSA Journal (2009) 1016, 1-10, 10p.
Fux Elie, Bire Ronel, Hess Philipp (2009). Comparative accumulation and composition of lipophilic marine biotoxins in passive samplers and in mussels (M. edulis) on the West Coast of Ireland. Harmful Algae, 8(3), 523-537. http://dx.doi.org/10.1016/j.hal.2008.10.007
Mccarron Pearse, Kilcoyne Jane, Miles Christopher O., Hess Philipp (2009). Formation of Azaspiracids-3,-4,-6, and-9 via Decarboxylation of Carboxyazaspiracid Metabolites from Shellfish. Journal Of Agricultural And Food Chemistry, 57(1), 160-169. http://dx.doi.org/10.1021/jf8025138
(2009) EFSA Panel on Contaminants in the Food Chain (CONTAM); Scientific Opinion on marine biotoxins in shellfish - Palytoxin group. European Commission, Ref. EFSA Journal 2009; 7(12):1393, 38p.
2008
(2008) Opinion of the Scientific Panel on Contaminants in the Food chain on a request from the European Commission on marine biotoxins in shellfish - yessotoxin group. European Commission, Ref. The EFSA Journal (2008) Journal number, 907, 1-62, 62p.
Alfonso Carmen, Rehmann Nils, Hess Philipp, Alfonso Amparo, Wandscheer Carolina B., Abuin Maria, Vale Carmen, Otero Paz, Vieytes Mercedes R., Botana Luis M. (2008). Evaluation of Various pH and Temperature Conditions on the Stability of Azaspiracids and Their Importance in Preparative Isolation and Toxicological Studies. Analytical Chemistry, 80(24), 9672-9680. http://dx.doi.org/10.1021/ac801506d
Fux E, Marcaillou-Le Baut Claire, Mondeguer Florence, Bire R, Hess Philipp (2008). Field and mesocosm trials on passive sampling for the study of adsorption and desorption behaviour of lipophilic toxins with a focus on OA and DTX1. Harmful Algae, 7(5), 574-583. Publisher's official version : http://dx.doi.org/10.1016/j.hal.2007.12.008 , Open Access version : http://archimer.ifremer.fr/doc/00000/4739/
Vale Paulo, Bire Ronel, Hess Philipp (2008). Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast. Toxicon, 51(8), 1449-1456. http://dx.doi.org/10.1016/j.toxicon.2008.03.022
Twiner Michael J., Rehmann Nils, Hess Philipp, Doucette Gregory J. (2008). Azaspiracid shellfish poisoning: A review on the chemistry, ecology, and toxicology with an emphasis on human health impacts. Marine Drugs, 6(2), 39-72. Publisher's official version : http://dx.doi.org/10.3390/md20080004 , Open Access version : http://archimer.ifremer.fr/doc/00077/18805/
Mccarron Pearse, Kilcoyne Jane, Hess Philipp (2008). Effects of cooking and heat treatment on concentration and tissue distribution of okadaic acid and dinophysistoxin-2 in mussels (Mytilus edulis). Toxicon, 51(6), 1081-1089. http://dx.doi.org/10.1016/j.toxicon.2008.01.009
Twiner Michael J., Ryan James C., Morey Jeanine S., Smith Kent J., Hammad Samar M., Van Dolah Frances M., Hess Philipp, Mcmahon Terry, Satake Masayuki, Yasumoto Takeshi, Doucette Gregory J. (2008). Transcriptional profiling and inhibition of cholesterol biosynthesis in human T lymphocyte cells by the marine toxin azaspiracid. Genomics, 91(3), 289-300. http://dx.doi.org/10.1016/j.ygeno.2007.10.015
Fux E., Rode D., Bire R., Hess Philipp (2008). Approaches to the evaluation of matrix effects in the liquid chromatography-mass spectrometry (LC-MS) analysis of three regulated lipophilic toxin groups in mussel matrix (Mytilus edulis). Food Additives And Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment, 25(8), 1024-1032. http://dx.doi.org/10.1080/02652030802008601
Rehmann Nils, Hess Philipp, Quilliam Michael A. (2008). Discovery of new analogs of the marine biotoxin azaspiracid in blue mussels (Mytilus edulis) by ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Communications In Mass Spectrometry, 22(4), 549-558. http://dx.doi.org/10.1002/rcm.3385