Mickael Le Gac

Mickael Le Gac

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Employer : Ifremer

Site : Brest

Postal address : Centre Bretagne - ZI de la Pointe du Diable - CS 10070 - 29280 Plouzané

URL : https://annuaire.ifremer.fr/cv/18498/en/

ORCID orcid icon : 0000-0001-6451-5781



Le Gac Mickael, Quere Julien, Rodriguez Francisco, Sechet Veronique (2022). RNA sequencing of 15 strains of Dinophysis, 2021. IFREMER. https://doi.org/10.12770/b8f4f6fc-fbb0-4f11-a63c-ef9482188f10
Quere Julien, Le Gac Mickael, Rodriguez Francisco (2022). RNA sequencing of 19 strains of Alexandrium minutum, 2021. IFREMER. https://doi.org/10.12770/f3f3a478-7385-45a8-b0e3-50222035bc58
Le Gac Mickael, Quere Julien, Rodriguez Francisco, Prigent Lea (2022). Coastal micro-eukaryote community metatranscriptomic reads. IFREMER. https://doi.org/10.12770/44f3c5bd-1286-443d-8b82-40ac0504066d
Mary Lou, Quere Julien, Le Gac Mickael (2022). RNA sequencing of 62 strains of Alexandrium minutum for Alex_genetic_linkage project, 2022. IFREMER. https://doi.org/10.12770/83a7d65c-816c-4c7b-9f56-c80bde39d879


Le Gac Mickael, Quere Julien, Rodriguez Francisco, Léa Prigent (2021). RNA sequencing of 143 phytoplankton community samples, 2021. IFREMER. https://doi.org//10.12770/e09498d3-cc68-4945-ae78-119d2dd32fcf


Le Gac Mickael (2017). Données transcriptomiques issues d'expériences de reproduction sexuée chez Alexandrium minutum. IFREMER. https://doi.org/10.12770/f721cb44-3792-472f-acab-95833c401c7c


Lema Anais Kimberley, Quere Julien, Le Gac Mickael (2016). Inter and intra-specific transcriptional and phenotypic responses of Pseudo-nitzschia under different nutrient conditions. IFREMER. https://doi.org/10.12770/78bba5d5-2112-467c-b35c-722992ded656
Le Gac Mickael, Metegnier Gabriel, Chomerat Nicolas, Malestroit Pascale, Quere Julien, Bouchez Olivier, Siano Raffaele, Destombe Christophe, Guillou Laure, Chapelle Annie (2016). Evolutionary processes and cellular functions underlying divergence in Alexandrium minutum . SEANOE . https://doi.org/10.17882/45445


Metegnier Gabriel, Quere Julien, Le Gac Mickael (2015). Metatranscriptomic sequences from Alexandrium minutum blooms sampled in situ in the bay of Brest (France) between 2013 and 2015. IFREMER. https://doi.org/10.12770/9d4131da-b33b-429b-9cdd-e7325b06f7d8



Le Gac Mickael, Mary Lou, Metegnier Gabriel, Quéré Julien, Siano Raffaele, Rodríguez Francisco, Destombe Christophe, Sourisseau Marc (2022). Strong population genomic structure of the toxic dinoflagellate Alexandrium minutum inferred from meta‐transcriptome samples . Environmental Microbiology , 24(12), 5966-5983 . Publisher's official version : https://doi.org/10.1111/1462-2920.16257 , Open Access version : https://archimer.ifremer.fr/doc/00800/91219/
Mary Lou, Quere Julien, Latimier Marie, Rovillon Georges-Augustin, Hégaret Helene, Réveillon Damien, Le Gac Mickael (2022). Genetic association of toxin production in the dinoflagellate Alexandrium minutum . Microbial Genomics , 8(11), 000879 (17p.) . Publisher's official version : https://doi.org/10.1099/mgen.0.000879 , Open Access version : https://archimer.ifremer.fr/doc/00801/91345/
Hariri Saeed, Plus Martin, Le Gac Mickael, Séchet Veronique, Revilla Marta, Sourisseau Marc (2022). Advection and Composition of Dinophysis spp. Populations Along the European Atlantic Shelf . Frontiers In Marine Science , 9, 914909 (14p.) . Publisher's official version : https://doi.org/10.3389/fmars.2022.914909 , Open Access version : https://archimer.ifremer.fr/doc/00787/89872/
Le Gac Mickael (2022). Structure et fonctions de la microdiversité au sein des communautés microbiennes: Focus sur le phytoplancton toxique . HDR.


Long Marc, Marie Dominique, Szymczak Jeremy, Toullec Jordan, Bigeard Estelle, Sourisseau Marc, Le Gac Mickael, Guillou Laure, Jauzein Cecile (2021). Dinophyceae can use exudates as weapons against the parasite Amoebophrya sp. (Syndiniales) . ISME Communications , 1(1), 34 (10p.) . Publisher's official version : https://doi.org/10.1038/s43705-021-00035-x , Open Access version : https://archimer.ifremer.fr/doc/00705/81679/
Geffroy Solene, Lechat Marc-Marie, Le Gac Mickael, Rovillon Georges-Augustin, Marie Dominique, Bigeard Estelle, Malo Florent, Amzil Zouher, Guillou Laure, Caruana Amandine (2021). From the sxtA4 Gene to Saxitoxin Production: What Controls the Variability Among Alexandrium minutum and Alexandrium pacificum Strains? Frontiers In Microbiology , 12, 613199 (16p.) . Publisher's official version : https://doi.org/10.3389/fmicb.2021.613199 , Open Access version : https://archimer.ifremer.fr/doc/00682/79402/
Caruana Amandine, Geffroy Solene, Lechat Marc-Marie, Le Gac Mickael, Rovillon Georges-Augustin, Marie Dominique, Bigeard Estelle, Malo Florent, Amzil Zouher, Guillou Laure (2021). Is sxtA4 gene discriminative for toxic Alexandrium species? What can we learn from its variability in copy number, expression and transcript isoform associated with toxin content? ICHA2021 - The 19th International Conference on Harmful Algae. October 11-15, 2021, La Paz, B.C.S. Mexico .


Seveno Julie, Even Yasmine, Le Gac Mickael (2020). Strong constitutive expression divergence among strains but no evidence of differential expression associated with sexual reproduction in Alexandrium minutum . Harmful Algae , 100, 101940 (12p.) . Publisher's official version : https://doi.org/10.1016/j.hal.2020.101940 , Open Access version : https://archimer.ifremer.fr/doc/00658/77022/
Caruana Amandine, Le Gac Mickael, Hervé Fabienne, Rovillon Georges-Augustin, Geffroy Solene, Malo Florent, Abadie Eric, Amzil Zouher (2020). Alexandrium pacificum and Alexandrium minutum: Harmful or environmentally friendly? Marine Environmental Research , 160, 105014 (10p.) . Publisher's official version : https://doi.org/10.1016/j.marenvres.2020.105014 , Open Access version : https://archimer.ifremer.fr/doc/00631/74305/
Metegnier Gabriel, Paulino Sauvann, Ramond Pierre, Siano Raffaele, Sourisseau Marc, Destombe Christophe, Le Gac Mickael (2020). Species specific gene expression dynamics during harmful algal blooms . Scientific Reports , 10(1), 6182 (14p.) . Publisher's official version : https://doi.org/10.1038/s41598-020-63326-8 , Open Access version : https://archimer.ifremer.fr/doc/00622/73390/
Ifremer. ODE/VIGIES (2020). Journées REPHY 2020. Nantes, 5 et 6 février 2020. Compilation des interventions et résumés . ODE/VIGIES/20-04 . https://archimer.ifremer.fr/doc/00612/72457/
García-Portela Maria, Reguera Beatriz, Gago Jesus, Le Gac Mickael, Rodríguez Francisco (2020). Uptake of Inorganic and Organic Nitrogen Sources by Dinophysis acuminata and D. acuta . Microorganisms , 8(2), 187 (14p.) . Publisher's official version : https://doi.org/10.3390/microorganisms8020187 , Open Access version : https://archimer.ifremer.fr/doc/00606/71770/


Sauvey Aurore, Claquin Pascal, Le Roy Bertrand, Le Gac Mickael, Fauchot Juliette (2019). Differential influence of life cycle on growth and toxin production of three Pseudo-nitzschia species (Bacillariophyceae) . Journal Of Phycology , 55(5), 1126-1139 . Publisher's official version : https://doi.org/10.1111/jpy.12898 , Open Access version : https://archimer.ifremer.fr/doc/00505/61679/
Lema Anais Kimberley, Metegnier Gabriel, Quéré Julien, Latimier Marie, Youenou Agnes, Lambert Christophe, Fauchot Juliette, Le Gac Mickael (2019). Inter and intra-specific transcriptional and phenotypic responses of Pseudo-nitzschia under different nutrient conditions . Genome Biology And Evolution , 11(3), 731-747 . Publisher's official version : https://doi.org/10.1093/gbe/evz030 , Open Access version : https://archimer.ifremer.fr/doc/00482/59392/


Siano Raffaele, Lassudrie Duchesne Malwenn, Delebecq Gaspard, Jauzein Cecile, Hess Philipp, Labry Claire, Le Gac Mickael, Mertens Kenneth, Mondeguer Florence, Sibat Manoella (2018). Paleoecology of marine protists : community dynamics and population adaptations revealed by ancient DNA metabarcoding and physiology of revived dinoflagellates . ISOP / PSA joint meeting. July 29th – August 2nd, 2018, Vancouver, University of British Columbia (Canada).
Siano Raffaele, Mondeguer Florence, Latimier Marie, Quere Julien, Sibat Manoella, Le Gac Mickael, Hess Philipp (2018). Dinoflagellate adaptation to coastal ecosystem variations revealed through metabolomic analyses of revived strains . ICHA2018 - 18th International Conference on Harmful Algae "From ecosystems to socio-ecosystems". 21-26 october 2018, Nantes, France .
Ifremer (2018). Apparition, préservation, maintien et évolution des organismes vivants dans le milieu marin . Rapport du groupe 3a - Réflexion stratégique 2017-2018 .


Lema Anais Kimberley, Latimier Marie, Nezan Elisabeth, Fauchot Juliette, Le Gac Mickael (2017). Inter and intra-specific growth and domoic acid production in relation to nutrient ratios and concentrations in Pseudo-nitzschia : phosphate an important factor . Harmful Algae , 64, 11-19 . Publisher's official version : https://doi.org/10.1016/j.hal.2017.03.001 , Open Access version : https://archimer.ifremer.fr/doc/00377/48849/


Klouch Khadidja, Schmidt Sabine, Christen Richard, Andrieux-Loyer Francoise, Le Gac Mickael, Hervio Heath Dominique, Nohemy Quiminet Zujaila, Quere Julien, Madec Lauriane, Bigeard Estelle, Guillou Laure, Siano Raffaele (2016). Multidecadal dynamics of protists and toxic dinoflagellates revealed from paleogenetic analyses of dated sediments of the Bay of Brest (France) . ICHA2016 - 17th International Conférence on Harmful Algae. 9-14 October 2016, Brazil.
Le Gac Mickael, Metegnier Gabriel, Chomerat Nicolas, Malestroit Pascale, Quere Julien, Bouchez Olivier, Siano Raffaele, Destombe Christophe, Guillou Laure, Chapelle Annie (2016). Evolutionary processes and cellular functions underlying divergence in Alexandrium minutum . Molecular Ecology , 25(20), 5129-5143 . Publisher's official version : https://doi.org/10.1111/mec.13815 , Open Access version : https://archimer.ifremer.fr/doc/00347/45857/
Klouch Khadidja, Schmidt Sabine, Andrieux-Loyer Francoise, Le Gac Mickael, Hervio-Heath Dominique, Qui-Minet Zujaila Nohemi, Quere Julien, Bigeard Estelle, Guillou Laure, Siano Raffaele (2016). Historical records from dated sediment cores reveal the multidecadal dynamic of the toxic dinoflagellate Alexandrium minutum in the Bay of Brest (France) . Fems Microbiology Ecology , 92(7), fiw101 . Publisher's official version : https://doi.org/10.1093/femsec/fiw101 , Open Access version : https://archimer.ifremer.fr/doc/00334/44516/
Plucain Jessica, Suau Antonia, Cruveiller Stephane, Medigue Claudine, Schneider Dominique, Le Gac Mickael (2016). Contrasting effects of historical contingency on phenotypic and genomic trajectories during a two-step evolution experiment with bacteria . Bmc Evolutionary Biology , 16, - . Publisher's official version : https://doi.org/10.1186/s12862-016-0662-8 , Open Access version : https://archimer.ifremer.fr/doc/00333/44447/
Hermabessiere Ludovic, Fabioux C., Lassudrie Malwenn, Boullot F., Long Marc, Lambert Christophe, Le Goic N., Gouriou Jeremie, Le Gac Mickael, Chapelle Annie, Soudant P., Hegaret Helene (2016). Influence of gametogenesis pattern and sex on paralytic shellfish toxin levels in triploid Pacific oyster Crassostrea gigas exposed to a natural bloom of Alexandrium minutum . Aquaculture , 455, 118-124 . Publisher's official version : https://doi.org/10.1016/j.aquaculture.2016.01.001 , Open Access version : https://archimer.ifremer.fr/doc/00307/41801/


Chapelle Annie, Le Gac Mickael, Labry Claire, Siano Raffaele, Quere Julien, Caradec Florian, Le Bec Claude, Nezan Elisabeth, Doner Anne, Gouriou Jeremie (2015). The Bay of Brest (France), a new risky site for toxic Alexandrium minutum blooms and PSP shellfish contamination . Harmful algae news , 51, 4-5 . Open Access version : https://archimer.ifremer.fr/doc/00278/38921/
Couceiro Lucia, Le Gac Mickael, Hunsperger Heather M., Mauger Stephane, Destombe Christophe, Cock J. Mark, Ahmed Sophia, Coelho Susana M., Valero Myriam, Peters Akira F. (2015). Evolution and maintenance of haploid-diploid life cycles in natural populations: The case of the marine brown alga Ectocarpus . Evolution , 69(7), 1808-1822 . https://doi.org/10.1111/evo.12702


Chapelle Annie, Le Bec Claude, Amzil Zouher, Dreanno Catherine, Guillou Laure, Klouch Khadidja, Labry Claire, Le Gac Mickael, Pineau-Guillou Lucia, Siano Raffaele, Abernot Chantal, Andrieux Francoise, Caradec Florian, Destombe Christophe, Dia A., Doner Anne, Duval Julia, Gouriou Jeremie, Lazure Pascal, Lebrun Luc, Le Gal Dominique, Malestroit Pascale, Petton Sebastien, Plus Martin, Quere Julien, Savar Veronique, Schmitt Sophie, Terre A., Youenou Agnes (2014). Étude sur la prolifération de la micro algue Alexandrium minutum en rade de Brest . R.INT.ODE/Dyneco/Pelagos 2014-07 . https://doi.org/10.13155/36487
Klouch Khadidja, Le Gac Mickael, Schmidt Sabine, Andrieux Francoise, Quere Julien, Bigeard Estelle, Guillou Laure, Siano Raffaele (2014). Invasions of Alexandrium minutum unveiled by sediment biological archives . ICHA 2014 New Zealand. The 16th International conference on Harmful Algae. 27-31 October 2014, Wellington, New Zealand .
Klouch Khadidja, Qui Minet Zujaila N., Andrieux-Loyer Françoise, Schmidt Sabine, Daniel Anne, Le Gac Mickael, Caradec Florian, Quere Julien, Youenou Agnes, Bigeard Estelle, Guillou Laure, Siano Raffaele (2014). Multidisciplinary paleoecological approach unveiled toxic phytoplankton species invasions and the eutrophication status of coastal ecosystems . ISOBAY 14 - XIV International Symposium on Oceanography of the Bay of Biscay, 11-13 june 2014, Bordeaux, France .
Chapelle Annie, Le Bec Claude, Siano Raffaele, Caradec Florian, Andrieux Francoise (2014). Étude sur la prolifération de la micro algue Alexandrium minutum en rade de Brest. Projet Daoulex. Rapport d’avancement n° 2 : Analyse des traces biologiques d’Alexandrium minutum dans les sédiments de la Rade de Brest. ODE/DYNECO/PELAGOS 2014-03 . https://archimer.ifremer.fr/doc/00191/30231/
Plucain Jessica, Hindre Thomas, Le Gac Mickael, Tenaillon Olivier, Cruveiller Stephane, Medigue Claudine, Leiby Nicholas, Harcombe William R., Marx Christopher J., Lenski Richard E., Schneider Dominique (2014). Epistasis and allele specificity in the emergence of a stable polymorphism in Escherichia coli . Science , 343(6177), 1366-1369 . https://doi.org/10.1126/science.1248688


Chapelle Annie, Le Bec Claude, Le Gac Mickael, Labry Claire, Amzil Zouher, Guillou Laure, Dreanno Catherine, Pineau-Guillou Lucia (2013). Etude sur la prolifération de la micro algue Alexandrium minutum en rade de Brest. Projet Daoulex. Rapport d’avancement n° 1 : Novembre 2013 . ODE/DYNECO/PELAGOS 2013-02 . https://archimer.ifremer.fr/doc/00191/30230/
Le Gac Mickael, Cooper Tim F., Cruveiller Stephane, Edigue Claudine M., Schneider Dominique (2013). Evolutionary history and genetic parallelism affect correlated responses to evolution . Molecular Ecology , 22(12), 3292-3303 . Publisher's official version : https://doi.org/10.1111/mec.12312 , Open Access version : https://archimer.ifremer.fr/doc/00148/25928/


Le Gac Mickael, Plucain Jessica, Hindre Thomas, Lenski Richard E., Schneider Dominique (2012). Ecological and evolutionary dynamics of coexisting lineages during a long-term experiment with Escherichia coli . Proceedings Of The National Academy Of Sciences Of The United States Of America , 109(24), 9487-9492 . https://doi.org/10.1073/pnas.1207091109


Hindre Thomas, Le Gac Mickael, Plucain Jessica, Wielgoss Sebastien, Gaffe Joel, Schneider Dominique (2010). L'évolution en action : rêve ou réalité ? Biofutur , (316), 52-56 .
Le Gac Mickael, Doebeli Michael (2010). Epistasis and frequency dependence influence the fitness of an adaptive mutation in a diversifying lineage . Molecular Ecology , 19(12), 2430-2438 . https://doi.org/10.1111/j.1365-294X.2010.04664.x
Le Gac Mickael, Doebeli Michael (2010). Environmental viscosity does not affect the evolution of cooperation during experimental evolution of colicigenic bacteria. Evolution , 64(2), 522-533 . https://doi.org/10.1111/j.1558-5646.2009.00814.x


Giraud Tatiana, Refregier Guislaine, Le Gac Mickael, de Vienne Damien M., Hood Michael E. (2008). Speciation in fungi . Fungal Genetics And Biology , 45(6), 791-802 . https://doi.org/10.1016/j.fgb.2008.02.001
Le Gac Mickael, Giraud T. (2008). Existence of a pattern of reproductive character displacement in Homobasidiomycota but not in Ascomycota . Journal Of Evolutionary Biology , 21(3), 761-772 . https://doi.org/10.1111/j.1420-9101.2008.01511.x
Refregier Guislaine, Le Gac Mickael, Jabbour Florian, Widmer Alex, Shykoff Jacqui A., Yockteng Roxana, Hood Michael E., Giraud Tatiana (2008). Cophylogeny of the anther smut fungi and their caryophyllaceous hosts: Prevalence of host shifts and importance of delimiting parasite species for inferring cospeciation . Bmc Evolutionary Biology , 8, - . Publisher's official version : https://doi.org/10.1186/1471-2148-8-100 , Open Access version : https://archimer.ifremer.fr/doc/00176/28694/
Le Gac Mickael, Brazas Michelle D., Bertrand Melanie, Tyerman Jabus G., Spencer Christine C., Hancock Robert E. W., Doebeli Michael (2008). Metabolic changes associated with adaptive diversification in escherichia coli . Genetics , 178(2), 1049-1060 . https://doi.org/10.1534/genctics.107.082040


Le Gac Mickael, Hood Michael E., Giraud Tatiana (2007). Evolution of reproductive isolation within a parasitic fungal species complex . Evolution , 61(7), 1781-1787 . https://doi.org/10.1111/j.1558-5646.2007.00144.x
Le Gac Mickael, Hood Michael E., Fournier Elisabeth, Giraud Tatiana (2007). Phylogenetic evidence of host-specific cryptic species in the anther smut fungus . Evolution , 61(1), 15-26 . https://doi.org/10.1111/j.1558-5646.2007.00002.x


Giraud Tatiana, Villareal Lorys Mma, Austerlitz Frederic, Le Gac Mickael, Lavigne Claire (2006). Importance of the life cycle in sympatric host race formation and speciation of pathogens . Phytopathology , 96(3), 280-287 . https://doi.org/10.1094/PHYTO-96-0280


Le Gac Mickael, Giraud Tatiana (2004). What is sympatric speciation in parasites? Trends In Parasitology , 20(5), 207-208 . https://doi.org/10.1016/j.pt.2004.02.003
Le Gac Mickael, Feral Jean-Pierre, Poulin Elie, Veyret Melanie, Chenuil Anne (2004). Identification of allopatric clades in the cosmopolitan ophiuroid species complex Amphipholis squamata (Echinodermata). The end of a paradox? Marine Ecology Progress Series , 278, 171-178 . https://doi.org/10.3354/meps278171


Chenuil A, Le Gac Mickael, Thierry M (2003). Fast isolation of microsatellite loci of very diverse repeat motifs by library enrichment in echinoderm species, Amphipholis squamata and Echinocardium cordatum . Molecular Ecology Notes , 3(2), 324-327 . https://doi.org/10.1046/j.1471-8286.2003.00434.x