Berthelier Jeremy, Saint-Jean Bruno, Casse Nathalie, Rouxel Catherine, Carrier Gregory (2019). Genomics data of a wild-type and a domesticated strains of the microalga Tisochrysis lutea and transposable elements annotation (v2) of the reference genome assembly . SEANOE . https://doi.org/10.17882/83584

Pageault Laura, Charrier Aurelie, Saint-Jean Bruno, Bougaran Gael, Mairet Francis, Stachowski-Haberkorn Sabine (2024). Cell Cycle Dynamics in the Microalga Tisochrysis lutea: Influence of Light Duration and Drugs . Cells , 13(22), 1925 (18p.) . Publisher's official version : https://doi.org/10.3390/cells13221925 , Open Access version : https://archimer.ifremer.fr/doc/00923/103491/

Carrier Gregory, Berthelier Jérémy, Maupetit Agathe, Nicolau Elodie, Marbouty Martial, Schreiber Nathalie, Charrier Aurelie, Carcopino Clemence, Leroi Laura, Saint-Jean Bruno (2024). Genetic and phenotypic intra-species diversity of alga Tisochrysis lutea reveals original genetic structure and domestication potential . European Journal Of Phycology , 59(1), 94-111 . Publisher's official version : https://doi.org/10.1080/09670262.2023.2249073 , Open Access version : https://archimer.ifremer.fr/doc/00855/96704/

Rumin Judith, Carrier Gregory, Rouxel Catherine, Charrier Aurelie, Raimbault Virginie, Cadoret Jean-Paul, Bougaran Gael, Saint-Jean Bruno (2023). Towards the optimization of genetic polymorphism with EMS-induced mutagenesis in Phaeodactylum tricornutum . Algal Research-biomass Biofuels And Bioproducts , 74, 103148 (8p.) . Publisher's official version : https://doi.org/10.1016/j.algal.2023.103148 , Open Access version : https://archimer.ifremer.fr/doc/00839/95111/

Berthelier Jérémy, Saint-Jean Bruno, Casse Nathalie, Bougaran Gael, Carrier Gregory (2023). Phenotype stability and dynamics of transposable elements in a strain of the microalga Tisochrysis lutea with improved lipid traits . Plos One , 18(4), e0284656 (20p.) . Publisher's official version : https://doi.org/10.1371/journal.pone.0284656 , Open Access version : https://archimer.ifremer.fr/doc/00835/94690/

Bonnefond H., Lie Y., Lacour Thomas, Saint-Jean Bruno, Carrier Gregory, Pruvost E., Talec A., Bernard O., Sciandra A. (2022). Dynamical Darwinian selection of a more productive strain of Tisochrysis lutea . Algal Research-biomass Biofuels And Bioproducts , 65, 102743 (8p.) . Publisher's official version : https://doi.org/10.1016/j.algal.2022.102743 , Open Access version : https://archimer.ifremer.fr/doc/00772/88374/

Pajot Anne, Lavaud Johann, Carrier Gregory, Garnier Matthieu, Saint-Jean Bruno, Rabilloud Noémie, Baroukh Caroline, Bérard Jean-Baptiste, Bernard Olivier, Marchal Luc, Nicolau Elodie (2022). The Fucoxanthin Chlorophyll a/c-Binding Protein in Tisochrysis lutea: Influence of Nitrogen and Light on Fucoxanthin and Chlorophyll a/c-Binding Protein Gene Expression and Fucoxanthin Synthesis . Frontiers In Plant Science , 13, 830069 (17p.) . Publisher's official version : https://doi.org/10.3389/fpls.2022.830069 , Open Access version : https://archimer.ifremer.fr/doc/00752/86392/

Huang Bing, Marchand Justine, Thiriet-Rupert Stanislas, Carrier Gregory, Saint-Jean Bruno, Lukomska Ewa, Moreau Brigitte, Morant-Manceau Annick, Bougaran Gael, Mimouni Virginie (2019). Betaine lipid and neutral lipid production under nitrogen or phosphorus limitation in the marine microalga Tisochrysis lutea (Haptophyta) . Algal Research-biomass Biofuels And Bioproducts , 40, 101506 (15p.) . Publisher's official version : https://doi.org/10.1016/j.algal.2019.101506 , Open Access version : https://archimer.ifremer.fr/doc/00492/60409/

Garnier Matthieu, Rogniaux Helene, Le Grand Fabienne, Bougaran Gael, Saint-Jean Bruno (2018). How nitrogen availability drives lipid composition in the haptophyte Tisochrysis lutea : new highlights . Lipids in the Ocean "Structure, function, ecological role and applications". 20-22 November 2018, Brest, France.

Mairet Francis, Baroukh Caroline, Berard Jean-Baptiste, Carrier Gregory, Charrier Aurelie, Garnier Matthieu, Kaas Raymond, Lukomska Ewa, Nicolau Elodie, Rouxel Catherine, Schreiber Nathalie, Saint-Jean Bruno, Bernard Olivier, Bougaran Gael (2018). Metabolic modelling of microalgae during nitrogen starvation . ICHA2018 - 18th International Conference on Harmful Algae "From ecosystems to socio-ecosystems". 21-26 october 2018, Nantes, France .

Berthelier Jeremy, Frances Tristan, Badawi Myriam, Jamailloux Veronique, Casse Nathalie, Saint-Jean Bruno, Carrier Gregory (2018). PiRATE v2: detection, classification and annotation of transposable elements of non-model organisms . Plant Epi/Genetics 2018 "plant epigenetics and transposable elements - from basic research to plant breeding". 29-31 October 2018, Angers .

Berthelier Jeremy, Frances Tristan, Badawi Myriam, Jamilloux Véronique, Casse Nathalie, Saint-Jean Bruno, Carrier Gregory (2018). PirateV2, detection, classification and annotation of TEs of non-model organisms . JOBIM 2018 - Journées Ouvertes Biologie, Informatique et Mathématiques. 3-6 juillet 2018, Marseille .

Berthelier Jeremy, Casse Nathalie, Daccord Nicolas, Jamilloux Veronique, Saint-Jean Bruno, Carrier Gregory (2018). A transposable element annotation pipeline and expression analysis reveal potentially active elements in the microalga Tisochrysis lutea . Bmc Genomics , 19(1), 378 (14p.) . Publisher's official version : https://doi.org/10.1186/s12864-018-4763-1 , Open Access version : https://archimer.ifremer.fr/doc/00441/55250/

Thiriet-Rupert Stanislas, Carrier Gregory, Trottier Camille, Eveillard D., Schoefs B., Bougaran Gael, Cadoret Jean-Paul, Chenais B., Saint-Jean Bruno (2018). Identification of transcription factors involved in the phenotype of a domesticated oleaginous microalgae strain of Tisochrysis lutea . Algal Research-biomass Biofuels And Bioproducts , 30, 59-72 . Publisher's official version : https://doi.org/10.1016/j.algal.2017.12.011 , Open Access version : https://archimer.ifremer.fr/doc/00418/52973/

Berthelier Jeremy, Casse Nathalie, Daccord Nicolas, Jamailloux Veronique, Saint-Jean Bruno, Carrier Gregory (2018). PiRATE: a Pipeline to Retrieve and Annotate TEs of non-model organisms . PAG XXVI (The Plant and Animal Genome Conference) - The Largest Ag-Genomics Meeting in the World. January 13-17, 2018, San Diego, USA .

Berthelier Jeremy, Casse Nathalie, Daccord Nicolas, Saint-Jean Bruno, Carrier Gregory (2018). PiRATE: a Pipeline to Retrieve and Annotate Transposable Elements in non-model organisms . PAG XXVI (The Plant and Animal Genome Conference) - The Largest Ag-Genomics Meeting in the World. January 13-17, 2018, San Diego, USA.

Berthelier Jeremy, Casse Nathalie, Daccord Nicolas, Jamilloux Veronique, Saint-Jean Bruno, Carrier Gregory (2017). PiRATE: a Pipeline to Retrieve and Annotate TEs in microalgal genomes . EMBO-EMBL 2017 "From Single- to Multiomics: Applications and Challenges in Data Integration". 12 - 14 Nov 2017, Heidelberg, Germany .

Ben Amor Faten, Elleuch Fatma, Ben Hlima Hajer, Garnier Matthieu, Saint-Jean Bruno, Barkallah Mohamed, Pichon Chantal, Abdelkafi Slim, Fendri Imen (2017). Proteomic Analysis of the Chlorophyta Dunaliella New Strain AL-1 Revealed Global Changes of Metabolism during High Carotenoid Production . Marine Drugs , 15(9), 293 (1-16) . Publisher's official version : https://doi.org/10.3390/md15090293 , Open Access version : https://archimer.ifremer.fr/doc/00402/51398/

Garnier Matthieu, Rogniaux H, Carrier Gregory, Berard Jean-Baptiste, Le Grand Fabienne, Cadoret Jean-Paul, Bougaran Gael, Saint-Jean Bruno (2017). Use of mutant strain, ecophysiological studies, and deep proteomic analysis reveal mechanisms of nitrogen acclimation and carbon partitioning in the haptophyte Tisochrysis lutea . IPC 11 - 11th International Phycologycal Congress “Challenges of the molecular era for algal research and the promise of bioprospecting”. August 13 to 19 2017, Szczecin, Poland .

Rouxel Catherine, Rumin Judith, Saint-Jean Bruno, Berard Jean-Baptiste, Marec Nadège, Cadoret Jean-Paul, Bougaran Gael (2017). Improving neutral lipid productivity by coupling mutagenesis to cytometry sorting . ISAP 2017 - 6th Congress of the International Society for Applied Phycology. 18th to 23rd June 2017, nantes .

Garnier Matthieu, Rogniaux H, Carrier Gregory, Berard Jean-Baptiste, Le Grand Fabienne, Lukomska Ewa, Rouxel Catherine, Schreiber Nathalie, Cadoret Jean-Paul, Bougaran Gael, Saint-Jean Bruno (2017). High sensibility to nitrogen and specific regulation of proteins involved carbon partitioning drive lipid over accumulation in Tisochrysis lutea 2X strain . ISAP 2017 - 6th Congress of the International Society for Applied Phycology. 18th to 23rd June 2017, Nantes .

Berthelier Jeremy, Casse Nathalie, Rouxel Catherine, Daccord Nicolas, Lhuissier M, Saint-Jean Bruno, Carrier Gregory (2017). TEs as markers of the genetic stability of domesticated microalgae after cryopreservation process . ISAP 2017 - 6th Congress of the International Society for Applied Phycolgy. 18th to 23rd June 2017, Nantes .

Garnier Matthieu, Bougaran Gael, Pavlovic Marija, Berard Jean-Baptiste, Carrier Gregory, Charrier Aurelie, Le Grand Fabienne, Lukomska Ewa, Rouxel Catherine, Schreiber Nathalie, Cadoret Jean-Paul, Rogniaux Helene, Saint-Jean Bruno (2016). Use of a lipid rich strain reveals mechanisms of nitrogen limitation and carbon partitioning in the haptophyte Tisochrysis lutea . Algal Research-biomass Biofuels And Bioproducts , 20, 229-248 . Publisher's official version : https://doi.org/10.1016/j.algal.2016.10.017 , Open Access version : https://archimer.ifremer.fr/doc/00356/46702/

Le Chevanton Myriam, Garnier Matthieu, Lukomska Ewa, Schreiber Nathalie, Cadoret Jean-Paul, Saint-Jean Bruno, Bougaran Gael (2016). Effects of nitrogen limitation on Dunaliella sp.–Alteromonas sp. interactions: from mutualistic to competitive relationships. Frontiers in Marine Science , 3(123), 1-11 . Publisher's official version : https://doi.org/10.3389/fmars.2016.00123 , Open Access version : https://archimer.ifremer.fr/doc/00344/45529/

Haberkorn Hansy, Saint-Jean Bruno, Berard Jean-Baptiste, Lukomska Ewa, Nicolau Elodie, Kaas Raymond, Schreiber Nathalie, Rouxel Catherine, Steyer Jean- Philippe, Sialve Bruno, Bougaran Gael (2016). Evaluating the potential of anaerobic digestates for marine microalgae production . OCEANEXT Interdisciplinary Conference, 8-10 juin 2016, Nantes .

Thiriet-Rupert Stanislas, Carrier Gregory, Chenais Benoit, Trottier Camille, Bougaran Gael, Cadoret Jean-Paul, Schoefs Benoit, Saint-Jean Bruno (2016). Transcription factors in microalgae: genome-wide prediction and comparative analysis . Bmc Genomics , 17(282), 1-16 . Publisher's official version : https://doi.org/10.1186/s12864-016-2610-9 , Open Access version : https://archimer.ifremer.fr/doc/00333/44403/

Thiriet-Rupert Stanislas, Carrier Gregory, Chenais Benoît, Trottier Camille, Eveillard Damien, Bougaran Gael, Cadoret Jean-Paul, Schoefs Benoît, Saint-Jean Bruno (2016). Reconstruction of gene network and regulatory network of an improved microalgae strain . aDVANCES IN SYSTEMS AND SYNTHETIC BIOLOGY :Modelling Complex Biological Systems in the Context of Genomics, Thematic Research School. March 21st to 25th 2016, Évry .

Berthelier Jeremy, Casse Nathalie, Saint-Jean Bruno, Carrier Gregory (2016). Annotation of TEs in the draft genome of the marine microalga Tisochrysis lutea . ICTE 2016 - International Congress on Transportable Elements. 16-19 april 2016, Saint-Malo, France .

Thiriet-Rupert Stanislas, Carrier Gregory, Chenais Benoît, Trottier Camille, Eveillard Damien, Bougaran Gael, Cadoret Jean-Paul, Schoefs Benoît, Saint-Jean Bruno (2015). Comprendre la production de lipides chez la microalgue Tisochrysis lutea . 13ème Forum Jeune-Recherche 2015, Université du Maine, Le Mans .

Garnier Matthieu, Bougaran Gael, Pavlovic M, Berard Jean-Baptiste, Carrier Gregory, Charrier Aurelie, Le Grand Fabienne, Lukomska Ewa, Rouxel Catherine, Schreiber Nathalie, Cadoret Jean-Paul, Rogniaux Helene, Saint-Jean Bruno (2015). Tisochrysis. lutea 2Xc1 strain is so fat. Why? EPC6 - 6th European Phycological Congress. 23-28 August 2015, London .

Charrier Aurelie Georgette, Berard Jean-Baptiste, Bougaran Gael, Carrier Gregory, Lukomska Ewa, Schreiber Nathalie, Fournier Flora, Charrier Aurelie, Rouxel Catherine, Garnier Matthieu, Cadoret Jean-Paul, Saint-Jean Bruno (2015). High-affinity nitrate/nitrite transporter genes (Nrt2) in Tisochrysis lutea: identification and expression analyses reveal some interesting specificities of Haptophyta microalgae . Physiologia Plantarum , 154(4), 572-590 . Publisher's official version : https://doi.org/10.1111/ppl.12330 , Open Access version : https://archimer.ifremer.fr/doc/00253/36467/

Rumin Judith, Bonnefond Hubert, Saint-Jean Bruno, Rouxel Catherine, Sciandra Antoine, Bernard Olivier, Cadoret Jean-Paul, Bougaran Gael (2015). The use of fluorescent Nile red and BODIPY for lipid measurement in microalgae . Biotechnology For Biofuels , 8(42), 1-16 . Publisher's official version : https://doi.org/10.1186/s13068-015-0220-4 , Open Access version : https://archimer.ifremer.fr/doc/00257/36823/

Rumin Judith, Rouxel Catherine, Saint-Jean Bruno, Marec Nadège, Desfrancois-Noel Juliette, Bougaran Gael (2015). Approches cytométriques à haut-débit chez les microalgues : optimiser la sélection de mutants riches en lipides neutres . AFC 2015 - XIXe congrès de l’Association Française de Cytométrie. 18-20 novembre 2015, Antibes Juan-les-Pins .

Rumin Judith, Saint-Jean Bruno, Rouxel Catherine, Cadoret Jean-Paul, Bougaran Gael (2015). Accumulation in Phaeodactylum Tricornutum Obtained by a Mutation-Selection Procedure . EPC6 - 6th European Phycological Congress. 23-28 August 2015, London .

Bougaran Gael, Saint-Jean Bruno (2014). Microalgues: de petits végétaux aux grandes promesses ! Biofutur , (360), 28-31 . Open Access version : https://archimer.ifremer.fr/doc/00252/36321/

Carrier Gregory, Berard Jean-Baptiste, Rouxel Catherine, Garnier Matthieu, Saint-Jean Bruno, Bougaran Gael (2014). Dynamique du génome et du phénotype de Tysochrysis lutea en réponses à des stress abiotiques utilisés en sélection variétale . Colloque annuel de la Société Phycologique de France. 24 Novembre 2014, Paris, France .

Carrier Gregory, Garnier Matthieu, Le Cunff Loic, Bougaran Gael, Probert Ian, de Vargas Colomban, Corre Erwan, Rouxel Catherine, Charrier Aurelie, Saint-Jean Bruno, Cadoret Jean-Paul (2014). Comparative transcriptome of wild type and selected strains of the microalgae Tisochrysis lutea provides insights into the genetic basis, lipid metabolism and the life cycle . Alg'n'Chem 2014 - Algae, new resources for Industry ? March 31 - April 3, 2014 Montpellier - France.

Garnier Matthieu, Carrier Gregory, Rogniaux Helene, Nicolau Elodie, Bougaran Gael, Saint-Jean Bruno, Cadoret Jean-Paul (2014). Comparative proteomics reveals proteins impacted by nitrogen deprivation in wild-type and high lipid-accumulating mutant strains of Tisochrysis lutea . Journal Of Proteomics , 105, 107-120 . Publisher's official version : https://doi.org/10.1016/j.jprot.2014.02.022 , Open Access version : https://archimer.ifremer.fr/doc/00179/29012/

Thiriet-Rupert Stanislas, Charrier Aurelie Georgette, Carrier Gregory, Schreiber Nathalie, Lukomska Ewa, Bougaran Gael, Saint-Jean Bruno, Chenais Benoît, Schoefs Benoît, Cadoret Jean-Paul (2014). Study of transcription factors involved in lipid accumulation-induced by nitrogen starvation in the microalgae Tisochrysis lutea . Alg'n'Chem 2014 - Algae, new resources for Industry ? March 31 - April 3, 2014 Montpellier - France .

Carrier Gregory, Garnier Matthieu, Le Cunff L, Bougaran Gael, Probert Ian, de Vargas Colomban, Corre Erwan, Rouxel Catherine, Charrier Aurelie, Saint-Jean Bruno, Cadoret Jean-Paul (2014). Comparative Transcriptome of Wild Type and Selected Strains of Tisochrysis lutea Provides Insights into the Genetic Basis, Lipid Metabolism and the Life Cycle . YAS2014 : Young Algaeneers symposium 2014. 3-5 Apr 2014 Montpellier-Narbonne (France) .

Carrier Gregory, Garnier Matthieu, Le Cunff Loic, Bougaran Gael, Probert Ian, de Vargas Colomban, Corre E, Cadoret Jean-Paul, Saint-Jean Bruno (2014). Comparative Transcriptome of Wild Type and Selected Strains of the Microalgae Tisochrysis lutea Provides Insights into the Genetic Basis, Lipid Metabolism and the Life Cycle . Plos One , 9(1), - . Publisher's official version : https://doi.org/10.1371/journal.pone.0086889 , Open Access version : https://archimer.ifremer.fr/doc/00175/28662/

Cadoret Jean-Paul, Bougaran Gael, Berard Jean-Baptiste, Carrier Gregory, Charrier Aurelie, Coulombier Noemie, Garnier Matthieu, Kaas Raymond, Le Dean Loic, Lukomska Ewa, Nicolau Elodie, Rouxel Catherine, Saint-Jean Bruno, Schreiber Nathalie (2014). Microalgues et Biotechnologie . In Valorisation et économie des ressources marines. Volume 4. Série Mer et Océan dirigée par André Mariotti sous la direction d'André Monaco et Patrick Prouzet. 2014. ISBN : 978-1-78405-003-0 . Chapitre 2, pp.65-112 .

Gastineau Romain, Davidovich Nikolai, Hansen Gert, Rines Jan, Wulff Angela, Kaczmarska Irena, Ehrman James, Hermann Dorothee, Maumus Florian, Hardivillier Yann, Leignel Vincent, Jacquette Boris, Meleder Vona, Hallegraeff Gustaaf, Yallop Marian, Perkins Rupert, Cadoret Jean-Paul, Saint-Jean Bruno, Carrier Gregory, Mouget Jean-Luc (2014). Haslea ostrearia-like Diatoms: Biodiversity out of the Blue . Advances in Botanical Research : Sea Plants , 71, 441-465 . https://doi.org/10.1016/B978-0-12-408062-1.00015-9

Garnier Matthieu, Carrier Gregory, Rogniaux Helene, Nicolau Elodie, Bougaran Gael, Saint-Jean Bruno, Cadoret Jean-Paul (2013). Use comparative proteomics on a selected microalgae provides candidates for biofuel production. EuPA 2013, 14-17 Octobre 2013, Saint-Malo, France . https://archimer.ifremer.fr/doc/00176/28735/

Marchetti Julie, Bougaran Gael, Jauffrais Thierry, Lefebvre Sebastien, Rouxel Catherine, Saint-Jean Bruno, Lukomska Ewa, Robert Rene, Cadoret Jean-Paul (2013). Effects of blue light on the biochemical composition and photosynthetic activity of Isochrysis sp. (T-iso) . Journal Of Applied Phycology , 25(1), 109-119 . Publisher's official version : https://doi.org/10.1007/s10811-012-9844-y , Open Access version : https://archimer.ifremer.fr/doc/00085/19599/

Cadoret Jean-Paul, Garnier Matthieu, Saint-Jean Bruno (2012). Microalgae, Functional Genomics and Biotechnology . Advances in Botanical Research , 64, 285-341 . Publisher's official version : https://doi.org/10.1016/B978-0-12-391499-6.00008-6 , Open Access version : https://archimer.ifremer.fr/doc/00125/23602/

Baiet Berengere, Burel Carole, Saint-Jean Bruno, Louvet Romain, Menu-Bouaouiche Laurence, Kiefer-Meyer Marie-Christine, Mathieu-Rivet Elodie, Lefebvre Thomas, Castel Helene, Carlier Aude, Cadoret Jean-Paul, Lerouge Patrice, Bardor Muriel (2011). N-Glycans of Phaeodactylum tricornutum Diatom and Functional Characterization of Its N-Acetylglucosaminyltransferase I Enzyme . Journal Of Biological Chemistry , 286(8), 6152-6164 . Publisher's official version : https://doi.org/10.1074/jbc.M110.175711 , Open Access version : https://archimer.ifremer.fr/doc/00031/14184/

Saint-Jean Bruno, Seveno-Carpentier Emilie, Alcon Carine, Neuhaus Jean-Marc, Paris Nadine (2010). The Cytosolic Tail Dipeptide Ile-Met of the Pea Receptor BP80 Is Required for Recycling from the Prevacuole and for Endocytosis . Plant Cell , 22(8), 2825-2837 . Publisher's official version : https://doi.org/10.1105/tpc.109.072215 , Open Access version : https://archimer.ifremer.fr/doc/00014/12525/

Bougaran Gael, Garnier Matthieu, Saint-Jean Bruno, Schreiber Nathalie, Cadoret Jean-Paul (2010). Intégration d’outils moléculaires et biochimiques pour l’étude de la physiologie des microalgues : Exemple du métabolisme azoté chez Isochrysis affinis galbana. Colloque "ALGUES, Filières du Futur !", 17 au 19 nov. 2010, Parc Techno. Biocitech, Paris .

Marchetti Julie, Jauffrais Thierry, Bougaran Gael, Lefebvre Sebastien, Saint-Jean Bruno, Lukomska Ewa, Robert Rene, Cadoret Jean-Paul (2010). Effet de la lumière bleue sur la composition biochimique et la réponse photosynthétique d’Isochrysis affinis galbana . Colloque "ALGUES, Filières du Futur !", 17 au 19 nov. 2010, Parc Techno. Biocitech, Paris .

Paris Nadine, Saint-Jean Bruno, Faraco Marianna, Krzeszowiec Weronika, Dalessandro Giuseppe, Neuhaus Jean-Marc, Di Sansebastiano Gian Pietro (2010). Expression of a glycosylated GFP as a bivalent reporter in exocytosis . Plant Cell Reports , 29(1), 79-86 . https://doi.org/10.1007/s00299-009-0799-7

Le Chevanton Myriam, Bougaran Gael, Garnier Matthieu, Schreiber Nathalie, Berard Jean-Baptiste, Kaas Raymond, Saint-Jean Bruno, Fouilland Eric, Cadoret Jean-Paul (2010). Sélection de souches bactériennes d’intérêt pour la culture de microalgues . Colloque "ALGUES, Filières du Futur !", 17 au 19 nov. 2010, Parc Techno. Biocitech, Paris .