: Research Interests
Infectious diseases are one of the major causes of human and animal morbidity, and they have impacts on the economy, public health, and the environment. By studying the diversity of the pathogens responsible for diseases we can get further insights into their spread and persistence within host communities and among vectors and we may glean valuable information that will aid prevention and control efforts.
I, therefore, have broad interests in molecular epidemiology and pathogen evolution, phylogeography, spatial and landscape genetics, and disease ecology.
I study evolutionary and epidemiological processes that shape bacterial and/or viral genetic diversity, spanning from studying small-scale transmissions histories and within host and/or vector evolutionary processes (reassortment, recombination and adaptation) to large-scale epidemic processes such as spatial dispersal and demographic variations (phylogeography and phylodynamics).
Research projects I am currently involved in are: SEA-MONITOR, MoPSeq-DB, MODHUS, ROME and PRIMOYSTER. I am also coordinating an ANR project named IDEAL.
Teaching
Currently : Supervision of J. Trillaud (MSc student)
2020-2023: Scientific supervision of C. Pelletier (PhD student) - Supervisor: B. Morga
2023: - Supervision of C. Battistel (MSc student)
- Supervision of F. Tronçin (BSc student)
2020-2022: Scientific supervision of A. Mesnil (PhD student) - Supervisors: M.A. Travers and D. Destoumieux-Garzon
2022: Supervision of Judith Doroy (BSc student)
2021-2022: Supervision of Jean-Christophe Mouren (MSc student)
2019: Member of jury, Bioinformatics MSc, Clermont-Auvergne University
2015-2018:
- Practical work in "Introduction to R" and "Advanced Statistics" courses - University of Glasgow
- Animation of discussion groups as part of a course on "Diseases ecology" - University of Glasgow
2016: Co-supervision of M. Wallace (MSc student) – Supervisor: R. Biek
2013: Co-supervision of M. Bisseux (MSc student) – Supervisor: X. Bailly
Bibliography
2024
Ubiqus , Certain Gregoire, Hattab Tarek, Brind'Amour Anik, Schull Quentin, Chouvelon Tiphaine, Lassudrie Malwenn, Pérez Agúndez José A., Le Pivert Olivier, Petitgas Pierre (2024). Journées scientifiques sur les réseaux trophiques 10-11 janvier 2024 .
Hoch Thierry, Madouasse Aurélien, Jacquot Maude, Wongnak Phrutsamon, Beugnet Fréderic, Bournez Laure, Cosson Jean-François, Huard Frédéric, Moutailler Sara, Plantard Olivier, Poux Valérie, René-Martellet Magalie, Vayssier-Taussat Muriel, Verheyden Hélène, Vourc’h Gwenaël, Chalvet-Monfray Karine, Agoulon Albert (2024). Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate . Peer Community Journal , 4, e2 (13p.) . Publisher's official version : https://doi.org/10.24072/pcjournal.355 , Open Access version : https://archimer.ifremer.fr/doc/00872/98349/
2023
Garcia Celine, Mesnil Aurelie, Jacquot Maude, Tourbiez Delphine, Degremont Lionel, Hocquet Juliette, Chollet Bruno, Serpin Delphine, Nadeau Aurelie, Noyer Mathilde, Girardin Frederic, Meirland Antoine, Ricard Morgane, Rocroy Mélanie, Travers Agnes (2023). Dynamics of Vibrio aestuarianus in wild cockle beds of Hauts-de-France . 21st EAFP International Conference on Diseases of Fish and Shellfish. 11th-14th September 2023, Aberdeen, UK.
Ifremer. Laboratoire de Génétique et Pathologie des Mollusques (2023). Report of the 2023 Annual Meeting and 14th Technical Workshop of National Reference Laboratories for Mollusc Diseases. La Tremblade, France, 3rd-5th of May 2023 .
Battistel Clementine (2023). Développement de MoPSeq-DB, une base de données en ligne pour partager, visualiser et analyser les données de séquences d’organismes pathogènes des mollusques marins . Rapport d'alternance. Master Bioinformatique .
Battistel Clementine, Mouren Jean Christophe, Morga Benjamin, Pelletier Camille, Canier Lydie, Garcia Celine, Arzul Isabelle, Leroi Laura, Durand Patrick, Chevignon Germain, Jacquot Maude (2023). MoPSeq-DB. Molluscs Pathogen Sequences DataBase . JOBIM 2023 - Journées Ouvertes en Biologie, Informatique et Mathématiques. 27 au 30 juin 2023, Nancy .
Mesnil Aurelie, Jacquot Maude, Garcia Celine, Tourbiez Delphine, Canier Lydie, Bidois Audrey, Dégremont Lionel, Cheslett Deborah, Geary Michelle, Vetri Alessia, Roque Ana, Furones Dolors, Garden Alison, Orozova Petya, Arzul Isabelle, Sicard Mathieu, Charriere Guillaume, Destoumieux Garzon Delphine, Travers Agnes (2023). Emergence and clonal expansion of Vibrio aestuarianus lineages pathogenic for oysters in Europe . Molecular Ecology , 32(11), 2869-2883 . Publisher's official version : https://doi.org/10.1111/mec.16910 , Open Access version : https://archimer.ifremer.fr/doc/00823/93481/
Garcia Celine, Tourbiez Delphine, Mesnil Aurelie, Jacquot Maude, Degremont Lionel, Hocquet Juliette, Chollet Bruno, Serpin Delphine, Nadeau Aurelie, Noyer Mathilde, Girardin Frederic, Devreker David, Meirland Antoine, Ricard Morgane, Rocroy Mélanie, Travers Agnes (2023). Dynamics of Vibrio aestuarianus in cockles in wild beds of Hauts-de-France . 2023 Annual Meeting of National Reference Laboratories for Mollusc Diseases.3-5th of May 2023 , La Tremblade, France .
Canier Lydie, Chollet Bruno, Serpin Delphine, Noyer Mathilde, Nadeau Aurelie, Lecadet Cyrielle, Jacquot Maude, Chevignon Germain, Garcia Celine, Arzul Isabelle (2023). EURL for mollusc diseases : 2022 activities & perspectives . 2023 Annual Meeting of National Reference Laboratories for Mollusc Diseases, La Tremblade, France, 3-5th of May 2023 .
2022
Dotto-Maurel Aurelie, Pelletier Camille, Morga Benjamin, Jacquot Maude, Faury Nicole, Dégremont Lionel, Bereszczynki Maëlis, Delmotte Jean, Escoubas Jean-Michel, Chevignon Germain (2022). Evaluation of tangential flow filtration coupled to long-read sequencing for ostreid herpesvirus type 1 genome assembly . Microbial Genomics , 8(11), 000895 (17p.) . Publisher's official version : https://doi.org/10.1099/mgen.0.000895 , Open Access version : https://archimer.ifremer.fr/doc/00804/91607/
Jacquot Maude, Mouren Jean Christophe, Battistel Clementine, Morga Benjamin, Pelletier Camille, Canier Lydie, Garcia Celine, Arzul Isabelle, Leroi Laura, Durand Patrick, Chevignon Germain (2022). MoPSeq-DB: a web platform to share, visualise and analyse sequence data of mollusc pathogens . ISEEMPD 2022 - International Symposium on Ecology and Evolution of Marine Parasites and Diseases. 15-18 November 2022, La Rochelle, France . https://archimer.ifremer.fr/doc/00827/93932/
Jacquot Maude, Wallace Megan A., Streicker Daniel G., Biek Roman (2022). Geographic Range Overlap Rather than Phylogenetic Distance Explains Rabies Virus Transmission among Closely Related Bat Species . Viruses-basel , 14(11), 2399 (13p.) . Publisher's official version : https://doi.org/10.3390/v14112399 , Open Access version : https://archimer.ifremer.fr/doc/00800/91229/
Doroy Judith (2022). Optimisation d'un protocole d'extraction d'ADN de tissus de mollusques inclus en bloc de paraffine . Rapport d'activité professionnelle. CNAM Rhône-Alpes / ESTBB .
Wongnak Phrutsamon, Bord Severine, Jacquot Maude, Agoulon Albert, Beugnet Frederic, Bournez Laure, Cebe Nicolas, Chevalier Adelie, Cosson Jean-Francois, Dambrine Naima, Hoch Thierry, Huard Frederic, Korboulewsky Nathalie, Lebert Isabelle, Madouasse Aurelien, Marell Anders, Moutailler Sara, Plantard Olivier, Pollet Thomas, Poux Valerie, Rene-Martellet Magalie, Vayssier-Taussat Muriel, Verheyden Helene, Vourc'h Gwenael, Chalvet-Monfray Karine (2022). Meteorological and climatic variables predict the phenology of Ixodes ricinus nymph activity in France, accounting for habitat heterogeneity . Scientific Reports , 12(1), 7833 (16p.) . Publisher's official version : https://doi.org/10.1038/s41598-022-11479-z , Open Access version : https://archimer.ifremer.fr/doc/00774/88614/
Delmotte Jean, Pelletier Camille, Morga Benjamin, Galinier Richard, Petton Bruno, Lamy Jean-Baptiste, Kaltz Oliver, Avarre Jean-Christophe, Jacquot Maude, Montagnani Caroline, Escoubas Jean Michel (2022). Genetic Diversity and Connectivity of the Ostreid Herpesvirus 1 Populations in France: A First Attempt to Phylogeographic Inference for a Marine Mollusc Disease . Virus Evolution , 8(1), veac039 (14p.) . Publisher's official version : https://doi.org/10.1093/ve/veac039 , Open Access version : https://archimer.ifremer.fr/doc/00766/87834/
Canier Lydie, Garcia Celine, Jacquot Maude, Chevignon Germain, Arzul Isabelle (2022). Report of the 2022 Annual Meeting of the National Reference Laboratories for Mollusc Diseases. Online meeting, 28-29th of March 2022 .
Canier Lydie, Chollet Bruno, Noyer Mathilde, Serpin Delphine, Nadeau Aurelie, Lecadet Cyrielle, Travers Agnes, Jacquot Maude, Chevignon Germain, Garcia Celine, Arzul Isabelle (2022). EURL for mollusc diseases : 2021 activities & perspectives . 2022 Annual Meeting of National Reference Laboratories for Mollusc Diseases. 28-29th of March 2022, online meeting .
Ifremer. EURL Mollusc Diseases (2022). Survey on first detections of the Bacteria Vibrio aestuarianus in Europe . Synthetic report of survey answers provided by EU National Reference Laboratories regarding the first detection of Vibrio aestuarianus in their country .
Mouren Jean Christophe (2022). MoPSeq-DB: une plateforme web pour partager, visualiser et analyser des données de séquences d'agents pathogènes de mollusques . Rapport d'alternance de Master 2, parcours Ingénierie Bioinformatique. Université de Nantes .
Garcia Celine, Chollet Bruno, Serpin Delphine, Noyer Mathilde, Nadeau Aurelie, Tourbiez Delphine, Mesnil Aurelie, Canier Lydie, Schwerdtle Pascal, Pelletier Camille, Morga Benjamin, Faury Nicole, Jacquot Maude, Chevignon Germain, Dotto-Maurel Aurelie, Travers Agnes, Heurtebise Serge, Lecadet Cyrielle, Betto Veronique, Arzul Isabelle (2022). Rapport annuel du Laboratoire National de Référence des Maladies des Mollusques Marins. Année 2021 . Convention relative aux actions de surveillance de la santé des mollusques marins Ifremer-DGAL n°21/1002311. RBE/SG2M/LGPMM .
Garcia Celine, Chollet Bruno, Serpin Delphine, Noyer Mathilde, Nadeau Aurelie, Tourbiez Delphine, Canier Lydie, Jacquot Maude, Chevignon Germain, Dotto-Maurel Aurelie, Schwerdtle Pascal, Faury Nicole, Pelletier Camille, Morga Benjamin, Travers Agnes, Mesnil Aurelie, Arzul Isabelle (2022). Laboratoire National de Référence des maladies des mollusques marins. Bilan 2021 . Journée des laboratoires agrées et reconnus pour les maladies des mollusques marins. 15 mars 2022 .
2021
Morga Benjamin, Jacquot Maude, Pelletier Camille, Chevignon Germain, Dégremont Lionel, Biétry Antoine, Pepin Jean-Francois, Heurtebise Serge, Escoubas Jean Michel, Bean Tim P., Rosani Umberto, Bai Chang-Ming, Renault Tristan, Lamy Jean-Baptiste (2021). Genomic Diversity of the Ostreid Herpesvirus Type 1 Across Time and Location and Among Host Species . Frontiers In Microbiology , 12, 711377 (13p.) . Publisher's official version : https://doi.org/10.3389/fmicb.2021.711377 , Open Access version : https://archimer.ifremer.fr/doc/00706/81762/
Mignotte Antoine, Garros Claire, Dellicour Simon, Jacquot Maude, Gilbert Marius, Gardès Laetitia, Balenghien Thomas, Duhayon Maxime, Rakotoarivony Ignace, de Wavrechin Maïa, Huber Karine (2021). High dispersal capacity of Culicoides obsoletus (Diptera: Ceratopogonidae), vector of bluetongue and Schmallenberg viruses, revealed by landscape genetic analyses . Parasites & Vectors , 14(1), 93 (14p.) . Publisher's official version : https://doi.org/10.1186/s13071-020-04522-3 , Open Access version : https://archimer.ifremer.fr/doc/00678/79022/
Garcia Celine, Chollet Bruno, Serpin Delphine, Noyer Mathilde, Nadeau Aurelie, Travers Agnes, Tourbiez Delphine, Mesnil Aurelie, Canier Lydie, Lupo Coralie, Arzul Isabelle, Schwerdtle Pascal, Menicot Samuel, Faury Nicole, Morga Benjamin, Degremont Lionel, Jacquot Maude, Chevignon Germain, Lecadet Cyrielle, Merou Nicolas, Betto Veronique, Bechemin Christian (2021). Rapport annuel du Laboratoire National de Référence des Maladies des Mollusques Marins. Année 2020 . Convention relative aux actions de surveillance de la santé des mollusques marins Ifremer-DGAL n°2020-087. RBE/SG2M/LGPMM .
2020
Pascall David J., Nomikou Kyriaki, Breard Emmanuel, Zientara Stephan, Filipe Ana Da Silva, Hoffmann Bernd, Jacquot Maude, Singer Joshua B., de Clercq Kris, Botner Anette, Sailleau Corinne, Viarouge Cyril, Batten Carrie, Puggioni Giantonella, Ligios Ciriaco, Savini Giovanni, Van Rijn Piet A., Mertens Peter P. C., Biek Roman, Palmarini Massimo (2020). "Frozen evolution" of an RNA virus suggests accidental release as a potential cause of arbovirus re-emergence . Plos Biology , 18(4), e3000673 (19p.) . Publisher's official version : https://doi.org/10.1371/journal.pbio.3000673 , Open Access version : https://archimer.ifremer.fr/doc/00667/77881/
2019
Jacquot Maude, Rao Pavuluri P., Yadav Sarita, Nomikou Kyriaki, Maan Sushila, Jyothi Y. Krishna, Reddy Narasimha, Putty Kalyani, Hemadri Divakar, Singh Karam P., Maan Narender Singh, Hegde Nagendra R., Mertens Peter, Biek Roman (2019). Contrasting selective patterns across the segmented genome of bluetongue virus in a global reassortment hotspot . Virus Evolution , 5(2), vez027 (14p.) . Publisher's official version : https://doi.org/10.1093/ve/vez027 , Open Access version : https://archimer.ifremer.fr/doc/00667/77882/
Fountain-Jones Nicholas M., Packer Craig, Jacquot Maude, Blanchet F. Guillaume, Terio Karen, Craft Meggan E. (2019). Endemic infection can shape exposure to novel pathogens: Pathogen co-occurrence networks in the Serengeti lions . Ecology Letters , 22(6), 904-913 . Publisher's official version : https://doi.org/10.1111/ele.13250 , Open Access version : https://archimer.ifremer.fr/doc/00667/77883/
2017
Fountain-Jones Nicholas M., Packer Craig, Troyer Jennifer L., Vanderwaal Kimberly, Robinson Stacie, Jacquot Maude, Craft Meggan E. (2017). Linking social and spatial networks to viral community phylogenetics reveals subtype-specific transmission dynamics in African lions . Journal Of Animal Ecology , 86(6), 1469-1482 . https://doi.org/10.1111/1365-2656.12751
Jacquot Maude, Nomikou Kyriaki, Palmarini Massimo, Mertens Peter, Biek Roman (2017). Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference . Proceedings of the Royal Society B: Biological Sciences , 284(1864), 20170919 (10p.) . Publisher's official version : https://doi.org/10.1098/rspb.2017.0919 , Open Access version : https://archimer.ifremer.fr/doc/00667/77880/
2016
Jacquot Maude, Abrial David, Gasqui Patrick, Bord Severine, Marsot Maud, Masseglia Sebastien, Pion Angelique, Poux Valerie, Zilliox Laurence, Chapuis Jean-Louis, Vourc'h Gwenael, Bailly Xavier (2016). Multiple independent transmission cycles of a tick-borne pathogen within a local host community . Scientific Reports , 6, 31273 (12p.) . Publisher's official version : https://doi.org/10.1038/srep31273 , Open Access version : https://archimer.ifremer.fr/doc/00667/77885/
Vourc'h G., Abrial D., Bord S., Jacquot Maude, Masseglia S., Poux V., Pisanu B., Bailly X., Chapuis J. -L. (2016). Mapping human risk of infection with Borrelia burgdorferi sensu lato, the agent of Lyme borreliosis, in a periurban forest in France . Ticks And Tick-borne Diseases , 7(5), 644-652 . https://doi.org/10.1016/j.ttbdis.2016.02.008
2014
Jacquot Maude, Gonnet Mathieu, Ferquel Elisabeth, Abrial David, Claude Alexandre, Gasqui Patrick, Choumet Valerie, Charras-Garrido Myriam, Garnier Martine, Faure Benjamin, Sertour Natacha, Dorr Nelly, de Goer Jocelyn, Vourc'h Gwenael, Bailly Xavier (2014). Comparative Population Genomics of the Borrelia burgdorferi Species Complex Reveals High Degree of Genetic Isolation among Species and Underscores Benefits and Constraints to Studying Intra-Specific Epidemiological Processes . Plos One , 9(4), e94384 (19p.) . Publisher's official version : https://doi.org/10.1371/journal.pone.0094384 , Open Access version : https://archimer.ifremer.fr/doc/00667/77887/
Jacquot Maude, Bisseux Maxime, Abrial David, Marsot Maud, Ferquel Elisabeth, Chapuis Jean-Louis, Vourc'h Gwenael, Bailly Xavier (2014). High-Throughput Sequence Typing Reveals Genetic Differentiation and Host Specialization among Populations of the Borrelia burgdorferi Species Complex that Infect Rodents . Plos One , 9(2), e88581 (9p.) . Publisher's official version : https://doi.org/10.1371/journal.pone.0088581 , Open Access version : https://archimer.ifremer.fr/doc/00667/77888/
Dataset
2023
Battistel Clémentine, Mouren Jean-Christophe, Morga Benjamin, Pelletier Camille, Canier Lydie, Garcia Celine, Arzul Isabelle, Auffret Pauline, Leroi Laura, Chevignon Germain, Durand Patrick, Jacquot Maude (2023). MoPSeq-DB: Mollusc Pathogen Sequence DataBase. IFREMER. https://doi.org//10.12770/52134702-4bbd-4c63-af34-9a2cde28e0cc